VeriMomHIGH RISK
Devo evitar valproic acid na gravidez? | VeriMom
Reviewed by VeriMom Editorial Team · Last reviewed
ECHA regulatory hazard statements
- •H360
- •H362
What to use instead
Pregnancy-safe ingredients that serve a similar function:
Pregnancy-safe products to use instead
Products built around the safer ingredients above, scored "no known risks" or "low risk".
Mew mew tweet
100Mew mew tweet Cedar Spruce Baking Soda Free
Avero
100Avero Solid Deodorant
L'Occitane
100L´Occitane Powder To-mousse Facial Exfoliator
Unknown
100schmidts here now
Sustain Yourself
100Sustain Yourself Natural Deodorant
Bitamin
100Bitamin Natural Deodorant N'orange
Routine
99Routine Sweet Jane Deodorant Jar
Laura Mercier
99Laura Mercier Tinted Moisturizer Broad Spectrum Spf 20 - Oil Free
Avril
99Déodorant baume
Salt of the Earth
99Salt of the Earth Unscented Natural Refillable Roll-on Deodorant
Sources & references
Authoritative references used to score this ingredient.
Alternativas seguras ao valproic acid na gravidez | VeriMom
Ingredientes — Ingredientes
Veja também
FAQ
- valproic acid é seguro durante a gravidez?
- Valproic acid is a well‑documented human teratogen (increased risk of neural tube and other major malformations and adverse neurodevelopmental outcomes) and is reported with H360 (may damage fertility or the unborn child) in ECHA/registration/SDS sources, which per your calibration maps to h=3. Mechanistically VPA is a histone deacetylase (HDAC) inhibitor with well‑characterised effects on gene expression and placental/embryonic development; placental effects and placental transfer have been reported. Topical cosmetic use would likely give low but measurable systemic exposure compared with therapeutic dosing (so e=1 for pregnancy). (Sources: PubMed systematic reviews and clinical teratology literature; ECHA registration/SDS showing H360; mechanistic reviews on HDAC inhibition).
- valproic acid é seguro durante a amamentação?
- Valproic acid is listed with H362 (may cause harm to breast‑fed children) in ECHA/SDS documents and transfers into breast milk in clinical/toxicology literature; the mechanistic actions that produce developmental neurotoxicity are the same basis for concern. For a cosmetic topical route maternal systemic levels would usually be low, so exposure via breastmilk from cosmetic use is expected to be low but measurable (e=1).
- valproic acid é seguro para a pele do bebê?
- Hazard remains high because VPA is a confirmed human developmental/teratogenic agent and H360/H362 are reported; mechanism (HDAC inhibition, disruption of developmental signalling) is well characterised. If VPA were present on infant skin (0–3 yrs) dermal absorption is more significant than in adults; per your rules increase exposure by +1 when measurable — cosmetic topical adult e=1 becomes baby e=2. There are no infant‑topical specific safety data showing safe use on baby skin.
- Como o VeriMom pontua valproic acid?
- O VeriMom pontua valproic acid em 13/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a valproic acid na gravidez?
- Veja nossa lista curada de alternativas seguras a valproic acid com base em função semelhante e classificação sem riscos conhecidos.
Verifique qualquer rótulo em 2 segundos
Baixe o VeriMom grátis — escaneie qualquer produto e veja a pontuação de segurança na gravidez instantaneamente.
Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.