Devo evitar tetrahydrofurfuryl alcohol na gravidez? | VeriMom
ECHA lists tetrahydrofurfuryl alcohol (CAS 97-99-4) with a harmonised classification Repr. 1B H360Df (may damage the unborn child), which is legally binding in the EU and justifies a Category 1 CMR hazard (h=3). Reproductive/developmental effects are reported in an OECD-style rat screening study (reduced pups, resorptions, effects on parental reproductive organs; NOAELs reported), supporting demonstrated in vivo developmental toxicity (m=2). For typical topical cosmetic use systemic absorption is possible but not expected to be high; therefore exposure for a cosmetic user is scored as low-to-measurable (e=1). Sources: ECHA harmonised classification and rat reproduction screening study.
ECHA regulatory hazard statements
- •H360DF
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- tetrahydrofurfuryl alcohol é seguro durante a gravidez?
- ECHA lists tetrahydrofurfuryl alcohol (CAS 97-99-4) with a harmonised classification Repr. 1B H360Df (may damage the unborn child), which is legally binding in the EU and justifies a Category 1 CMR hazard (h=3). Reproductive/developmental effects are reported in an OECD-style rat screening study (reduced pups, resorptions, effects on parental reproductive organs; NOAELs reported), supporting demonstrated in vivo developmental toxicity (m=2). For typical topical cosmetic use systemic absorption is possible but not expected to be high; therefore exposure for a cosmetic user is scored as low-to-measurable (e=1). Sources: ECHA harmonised classification and rat reproduction screening study.
- tetrahydrofurfuryl alcohol é seguro durante a amamentação?
- Harmonised Repr. 1B (H360Df) applies irrespective of exposure route and therefore indicates a high hazard for lactating people (h=3). Mechanistic evidence is from in vivo reproductive/developmental findings in animals (m=2). There are no high-quality lactation-transfer data; for typical cosmetic topical use systemic exposure is likely low-to-measurable (e=1), but if significant systemic exposure occurs transfer to milk cannot be ruled out.
- tetrahydrofurfuryl alcohol é seguro para a pele do bebê?
- Hazard remains high (h=3) because of the harmonised H360Df classification. Mechanistic rating is based on demonstrated in vivo developmental/reproductive effects in animals (m=2). Exposure for infants 0–3 years is increased by one point per your instructions because of immature barrier and higher SA:BW; therefore e is increased to 2 (moderate exposure potential) even if adult topical exposure would be low.
- Como o VeriMom pontua tetrahydrofurfuryl alcohol?
- O VeriMom pontua tetrahydrofurfuryl alcohol em 20/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a tetrahydrofurfuryl alcohol na gravidez?
- Veja nossa lista curada de alternativas seguras a tetrahydrofurfuryl alcohol com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.