Devo evitar oxyquinoline na gravidez? | VeriMom
Quinolin-8-ol (oxyquinoline, CAS 148-24-3) has an EU harmonised classification as a reproductive toxicant (Repr. 1B — H360D: “may damage the unborn child”), which by your scoring rules requires h=3. Mechanistic data linking a specific reproductive pathway are limited (mutagenicity was reported in some assays but no well‑characterised developmental mechanism), so m is scored 1 (theoretical/limited). For typical topical cosmetic use (used at ≤1% in formulations per CIR), dermal uptake is plausible but not high, so exposure (e) for pregnancy is scored 1 (low but measurable). (Sources: ECHA/EUR‑Lex harmonised classification; CIR safety assessment.).
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- oxyquinoline é seguro durante a gravidez?
- Quinolin-8-ol (oxyquinoline, CAS 148-24-3) has an EU harmonised classification as a reproductive toxicant (Repr. 1B — H360D: “may damage the unborn child”), which by your scoring rules requires h=3. Mechanistic data linking a specific reproductive pathway are limited (mutagenicity was reported in some assays but no well‑characterised developmental mechanism), so m is scored 1 (theoretical/limited). For typical topical cosmetic use (used at ≤1% in formulations per CIR), dermal uptake is plausible but not high, so exposure (e) for pregnancy is scored 1 (low but measurable). (Sources: ECHA/EUR‑Lex harmonised classification; CIR safety assessment.).
- oxyquinoline é seguro durante a amamentação?
- Because the substance has a harmonised Repr.1B/H360D classification (systemic reproductive hazard), the hazard to nursing is scored h=3 under your rules. There is no clear, well‑established mechanism specific to lactational transfer (m=1). Dermal cosmetic use gives low but potentially measurable systemic exposure (e=1), so transfer into milk cannot be excluded at trace levels; no robust human milk data were found in the reviewed sources.
- oxyquinoline é seguro para a pele do bebê?
- Do not increase hazard or mechanism absent infant‑specific data, so h=3 and m=1 as above. Because infant skin has higher permeability and surface‑area‑to‑weight, exposure score is increased by +1 from adult (adult e=1 → infant e=2), meaning moderate concern for systemic uptake from topical application to infant skin. No infant‑specific toxicokinetic or outcome studies were identified.
- Como o VeriMom pontua oxyquinoline?
- O VeriMom pontua oxyquinoline em 27/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a oxyquinoline na gravidez?
- Veja nossa lista curada de alternativas seguras a oxyquinoline com base em função semelhante e classificação sem riscos conhecidos.
Verifique qualquer rótulo em 2 segundos
Baixe o VeriMom grátis — escaneie qualquer produto e veja a pontuação de segurança na gravidez instantaneamente.
Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.