Devo evitar methyl acetamide na gravidez? | VeriMom
ECHA has a harmonised Classification & Labelling entry for N‑methylacetamide (CAS 79‑16‑3) as Repr.1B H360D (“May damage the unborn child”), which is a legally binding EU classification indicating developmental toxicity — by your calibration H360 → h=3. There is no well‑characterized molecular mechanism in the regulatory summaries, so mechanism is scored as theoretical/limited evidence (m=1). Dermal/topical systemic exposure data for cosmetic uses are not available in the regulatory summaries, so exposure from cosmetics is scored as low but measurable (e=1). (Sources: ECHA harmonised classification and ECHA substance profile; PubChem regulatory summary).
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- methyl acetamide é seguro durante a gravidez?
- ECHA has a harmonised Classification & Labelling entry for N‑methylacetamide (CAS 79‑16‑3) as Repr.1B H360D (“May damage the unborn child”), which is a legally binding EU classification indicating developmental toxicity — by your calibration H360 → h=3. There is no well‑characterized molecular mechanism in the regulatory summaries, so mechanism is scored as theoretical/limited evidence (m=1). Dermal/topical systemic exposure data for cosmetic uses are not available in the regulatory summaries, so exposure from cosmetics is scored as low but measurable (e=1). (Sources: ECHA harmonised classification and ECHA substance profile; PubChem regulatory summary).
- methyl acetamide é seguro durante a amamentação?
- The harmonised Repr.1B / H360D classification applies to developmental toxicity and is the governing regulatory flag for reproductive/developmental hazard and therefore is applied for lactation context as well (h=3). No specific mechanistic or lactation transfer studies were identified in the searched authoritative databases (m=1). No quantitative dermal absorption or milk‑transfer data were found for cosmetic use; systemic exposure from topical use is assumed low but measurable (e=1).
- methyl acetamide é seguro para a pele do bebê?
- Because the substance carries a harmonised H360D classification (developmental toxicant; Repr.1B) the hazard score is h=3 per your calibration. Mechanistic information is limited (m=1). For exposure, infant skin has higher absorption; in the absence of dermal absorption data for cosmetic formulations, increase exposure by +1 for baby skin (adult e=1 → baby e=2). No infant‑specific safety data were located. (Sources: ECHA harmonised CLP; ECHA substance information; PubChem.)
- Como o VeriMom pontua methyl acetamide?
- O VeriMom pontua methyl acetamide em 27/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a methyl acetamide na gravidez?
- Veja nossa lista curada de alternativas seguras a methyl acetamide com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.