Devo evitar methoxyethanol na gravidez? | VeriMom
2‑Methoxyethanol (CAS 109‑86‑4, EGME) has a harmonised EU classification for reproductive toxicity (Repr. 1B / H360FD) and multiple animal studies (rats, mice) showing fetal/developmental effects and teratogenicity; it is metabolised to methoxyacetic acid which mediates these effects. (ECHA substance & CLP background; rat developmental studies). Sources: ECHA substance profile and CLP background (harmonised Repr.1B/H360FD) and peer‑reviewed animal studies (PubMed). (https://echa.europa.eu/substance-information/-/substanceinfo/100.003.377; https://echa.europa.eu/documents/10162/aade66ad-5922-8029-d9a5-ea38c1bc25f3; https://pubmed.ncbi.nlm.nih.gov/2755424/).
ECHA regulatory hazard statements
- •H360FD
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- methoxyethanol é seguro durante a gravidez?
- 2‑Methoxyethanol (CAS 109‑86‑4, EGME) has a harmonised EU classification for reproductive toxicity (Repr. 1B / H360FD) and multiple animal studies (rats, mice) showing fetal/developmental effects and teratogenicity; it is metabolised to methoxyacetic acid which mediates these effects. (ECHA substance & CLP background; rat developmental studies). Sources: ECHA substance profile and CLP background (harmonised Repr.1B/H360FD) and peer‑reviewed animal studies (PubMed). (https://echa.europa.eu/substance-information/-/substanceinfo/100.003.377; https://echa.europa.eu/documents/10162/aade66ad-5922-8029-d9a5-ea38c1bc25f3; https://pubmed.ncbi.nlm.nih.gov/2755424/).
- methoxyethanol é seguro durante a amamentação?
- The hazard to reproduction/lactation is supported by harmonised classification and animal data; metabolism to methoxyacetic acid is a demonstrated mechanism. Systemic absorption is required for milk transfer; for cosmetic topical use systemic exposure is expected to be low but measurable, so breastfeeding exposure is possible if systemic absorption occurs (regulatory/animal data indicate systemic toxicity after inhalation/oral/dermal routes). (ECHA; IRIS/occupational reviews). (https://echa.europa.eu/substance-information/-/substanceinfo/100.003.377; https://cfpub.epa.gov/ncea/iris/iris_documents/documents/subst/0525_summary.pdf; https://www.cdc.gov/niosh/docs/83-112/default.html).
- methoxyethanol é seguro para a pele do bebê?
- Hazard and mechanism are the same (harmonised reprotoxic classification and demonstrated metabolite‑mediated effects). Dermal/topical exposure on infant skin results in higher exposure ranking than adults because infant skin has higher surface‑area‑to‑weight and an immature barrier; therefore exposure score is increased by +1 (adult e=1 → baby e=2). Regulatory/animal evidence supports systemic developmental toxicity; avoid use on infant skin. (ECHA; occupational reviews; IRIS). (https://echa.europa.eu/substance-information/-/substanceinfo/100.003.377; https://www.cdc.gov/niosh/docs/83-112/default.html; https://cfpub.epa.gov/ncea/iris/iris_documents/documents/subst/0525_summary.pdf).
- Como o VeriMom pontua methoxyethanol?
- O VeriMom pontua methoxyethanol em 20/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a methoxyethanol na gravidez?
- Veja nossa lista curada de alternativas seguras a methoxyethanol com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.