Devo evitar methoxydiglycol na gravidez? | VeriMom
ECHA lists diethylene glycol monomethyl ether (methoxydiglycol, CAS 111-77-3) with a harmonised CLP classification for reproductive toxicity (H360 - may damage fertility or the unborn child), which places it in the highest hazard band for developmental/reproductive effects. Animal and mechanistic work show it is metabolised to methoxyacetic acid, a metabolite implicated in reproductive/developmental toxicity in multiple studies, supporting a demonstrated mechanism. Dermal/topical use gives measurable systemic absorption for small glycols used as solvents, so exposure from cosmetics is non‑negligible (moderate). ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- methoxydiglycol é seguro durante a gravidez?
- ECHA lists diethylene glycol monomethyl ether (methoxydiglycol, CAS 111-77-3) with a harmonised CLP classification for reproductive toxicity (H360 - may damage fertility or the unborn child), which places it in the highest hazard band for developmental/reproductive effects. Animal and mechanistic work show it is metabolised to methoxyacetic acid, a metabolite implicated in reproductive/developmental toxicity in multiple studies, supporting a demonstrated mechanism. Dermal/topical use gives measurable systemic absorption for small glycols used as solvents, so exposure from cosmetics is non‑negligible (moderate). ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
- methoxydiglycol é seguro durante a amamentação?
- Because the substance has a harmonised H360 reproductive classification and is metabolised to methoxyacetic acid (a known reproductive toxicant), there is concern for transfer to nursing infants; advisory bodies note uncertainty but flag lactation as a relevant route and the absence of data on milk levels. Dermal/topical use can produce systemic levels (measurable), so breastfeeding exposure cannot be ruled out. ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
- methoxydiglycol é seguro para a pele do bebê?
- Hazard (H360) remains highest (h=3) due to harmonised CLP classification and animal evidence. Mechanistic concern (metabolism to methoxyacetic acid) is demonstrated. Exposure (e) is increased by +1 for infants (per your instruction): because the compound is a small, moderately skin‑permeable solvent with measurable dermal uptake in adults, infant skin (higher SA:weight and immature barrier) raises likely systemic exposure to high. ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
- Como o VeriMom pontua methoxydiglycol?
- O VeriMom pontua methoxydiglycol em 13/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a methoxydiglycol na gravidez?
- Veja nossa lista curada de alternativas seguras a methoxydiglycol com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.