Devo evitar methotrexate na gravidez? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

Pregnancy-safe products to use instead

Products built around the safer ingredients above, scored "no known risks" or "low risk".

Mew mew tweet

100

Mew mew tweet Cedar Spruce Baking Soda Free

Avero

100

Avero Solid Deodorant

L'Occitane

100

L´Occitane Powder To-mousse Facial Exfoliator

Unknown

100

schmidts here now

Sustain Yourself

100

Sustain Yourself Natural Deodorant

Bitamin

100

Bitamin Natural Deodorant N'orange

Routine

99

Routine Sweet Jane Deodorant Jar

Laura Mercier

99

Laura Mercier Tinted Moisturizer Broad Spectrum Spf 20 - Oil Free

Avril

99

Déodorant baume

Salt of the Earth

99

Salt of the Earth Unscented Natural Refillable Roll-on Deodorant

Alternativas seguras ao methotrexate na gravidez | VeriMom

Ingredientes — Ingredientes

Veja também

• methotrexate é seguro durante a gestação?
• methotrexate é seguro para bebês?
• Quais são as alternativas seguras a methotrexate na gestação?

FAQ

methotrexate é seguro durante a gravidez?

Methotrexate is a well‑known human teratogen and is contraindicated in pregnancy (FDA labeling: Pregnancy Category X) and causes fetal harm via folate antagonism (dihydrofolate reductase inhibition) with documented fetal malformations and pregnancy loss; this is a harmonised/high‑level reproductive hazard. Topical cosmetic use would give negligible systemic exposure in routine cosmetic scenarios, so exposure from cosmetic use is expected to be negligible. (Sources: FDA label; peer‑reviewed teratology literature; regulatory listings).

methotrexate é seguro durante a amamentação?

Methotrexate is contraindicated in nursing mothers in drug labeling because of potential for serious adverse effects in the breastfed infant and its systemic distribution; mechanism (DHFR inhibition/antifolate) is established. For a cosmetic topical use scenario, maternal systemic exposure from a cosmetic product would be negligible, so milk transfer from cosmetic use is not expected.

methotrexate é seguro para a pele do bebê?

Hazard is high (harmonised/regulatory teratogen/antimetabolite). For direct application to baby (0–3 yr) the immature barrier raises exposure compared with adults: even if adult topical absorption is negligible for a highly polar drug, the guidance requires raising the exposure score by +1 for baby skin when measurable absorption is possible. Therefore exposure = 1 for baby skin; mechanism (antifolate/DHFR inhibition) is well characterized.

Como o VeriMom pontua methotrexate?

O VeriMom pontua methotrexate em 20/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.

Quais são as alternativas seguras a methotrexate na gravidez?

Veja nossa lista curada de alternativas seguras a methotrexate com base em função semelhante e classificação sem riscos conhecidos.