VeriMomDevo evitar imidazole na gravidez? | VeriMom
Imidazole (CAS 288-32-4) is listed by ECHA with a harmonised classification for developmental toxicity (Category 1B, H360D), which by your scoring rules is H360-level evidence -> h=3. The mechanistic basis for the classification is not well‐characterised in publicly available dossiers, so mechanism is scored as theoretical/uncertain (m=1). Dermal/topical cosmetic exposure would likely give low but measurable systemic exposure for an adult (e=1) unless formulation/route increases uptake; this is supported by ECHA/EU classification and multiple safety data sheets listing H360D.
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- imidazole é seguro durante a gravidez?
- Imidazole (CAS 288-32-4) is listed by ECHA with a harmonised classification for developmental toxicity (Category 1B, H360D), which by your scoring rules is H360-level evidence -> h=3. The mechanistic basis for the classification is not well‐characterised in publicly available dossiers, so mechanism is scored as theoretical/uncertain (m=1). Dermal/topical cosmetic exposure would likely give low but measurable systemic exposure for an adult (e=1) unless formulation/route increases uptake; this is supported by ECHA/EU classification and multiple safety data sheets listing H360D.
- imidazole é seguro durante a amamentação?
- Because imidazole has a harmonised developmental/teratogenic classification (H360D, Category 1B) the hazard for lactation/breastfeeding is elevated and scored h=3 per your rule for H360-level evidence. No specific human milk transfer or breastfeeding studies were identified in the sources consulted, so mechanistic evidence is limited (m=1). Maternal topical use would most likely give low but measurable systemic exposure (e=1) in adults; therefore potential transfer in milk cannot be excluded.
- imidazole é seguro para a pele do bebê?
- Hazard remains H360-level (h=3) because of ECHA harmonised developmental classification. Mechanistic data are limited (m=1). For baby skin (0–3 yr) exposure scoring increases by +1 compared with adults when the adult exposure is measurable: adult e=1 -> infant e=2 because infant skin has higher surface-area-to-weight and an immature barrier, increasing potential absorption.
- Como o VeriMom pontua imidazole?
- O VeriMom pontua imidazole em 27/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a imidazole na gravidez?
- Veja nossa lista curada de alternativas seguras a imidazole com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.