VeriMomDevo evitar formamidine sulfinic acid na gravidez? | VeriMom
Animal reproductive/developmental data in the OECD SIDS report show reduced litter size and effects on corpora lutea at high doses and a NOAEL for reproductive performance of 15 mg/kg bw in rats, so reproductive hazard is suspected (h=2). No harmonised EU CMR Category 1 (H360/H350/H340) is listed for this substance on ECHA; the reproductive effects appear secondary to maternal toxicity rather than a characterised endocrine mechanism, so mechanism is scored as theoretical/demonstrated by animal study (m=1). Dermal/topical exposure is expected to give low but measurable systemic exposure (low logP, water soluble), so exposure score is 1. Sources: OECD SIDS (reproduction data) and ECHA substance record.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- formamidine sulfinic acid é seguro durante a gravidez?
- Animal reproductive/developmental data in the OECD SIDS report show reduced litter size and effects on corpora lutea at high doses and a NOAEL for reproductive performance of 15 mg/kg bw in rats, so reproductive hazard is suspected (h=2). No harmonised EU CMR Category 1 (H360/H350/H340) is listed for this substance on ECHA; the reproductive effects appear secondary to maternal toxicity rather than a characterised endocrine mechanism, so mechanism is scored as theoretical/demonstrated by animal study (m=1). Dermal/topical exposure is expected to give low but measurable systemic exposure (low logP, water soluble), so exposure score is 1. Sources: OECD SIDS (reproduction data) and ECHA substance record.
- formamidine sulfinic acid é seguro durante a amamentação?
- No human breastfeeding-specific data were found. Animal reproductive data (OECD SIDS) that indicate effects on reproductive performance support a suspected hazard during lactation (h=2). Mechanistic evidence is limited (m=1). Expected systemic exposure from topical use is low but measurable (e=1); transfer in milk is not documented.
- formamidine sulfinic acid é seguro para a pele do bebê?
- No infant-specific studies were identified. Because animal reproductive/developmental toxicity exists (OECD SIDS), the same suspected hazard rating (h=2) is applied. Mechanistic data remain limited (m=1). Exposure for infants (0–3 yr) is increased by one point relative to adults because immature skin has higher absorption; therefore exposure is e=2 (adult e=1 → baby +1).
- Como o VeriMom pontua formamidine sulfinic acid?
- O VeriMom pontua formamidine sulfinic acid em 27/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a formamidine sulfinic acid na gravidez?
- Veja nossa lista curada de alternativas seguras a formamidine sulfinic acid com base em função semelhante e classificação sem riscos conhecidos.
Verifique qualquer rótulo em 2 segundos
Baixe o VeriMom grátis — escaneie qualquer produto e veja a pontuação de segurança na gravidez instantaneamente.
Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.