VeriMomDevo evitar estradiol na gravidez? | VeriMom
Estradiol (17β‑estradiol, CAS 50-28-2) carries harmonised reproductive hazard classification (H360—may damage fertility or the unborn child) in EU classification sources and product SDSs, and medicinal product labeling/clinical guidance list estradiol as contraindicated in pregnancy. Estrogens cross the placenta and maternal/experimental studies show excess maternal estradiol alters fetal development. Topical/transdermal estradiol formulations are known to give systemic exposure, so topical cosmetic application with appreciable systemic absorption would expose the fetus. (ECHA classification/SDS; DailyMed drug labeling; animal and human studies).
ECHA regulatory hazard statements
- •H360
- •H360FD
- •H361
- •H362
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- estradiol é seguro durante a gravidez?
- Estradiol (17β‑estradiol, CAS 50-28-2) carries harmonised reproductive hazard classification (H360—may damage fertility or the unborn child) in EU classification sources and product SDSs, and medicinal product labeling/clinical guidance list estradiol as contraindicated in pregnancy. Estrogens cross the placenta and maternal/experimental studies show excess maternal estradiol alters fetal development. Topical/transdermal estradiol formulations are known to give systemic exposure, so topical cosmetic application with appreciable systemic absorption would expose the fetus. (ECHA classification/SDS; DailyMed drug labeling; animal and human studies).
- estradiol é seguro durante a amamentação?
- Harmonised/label information and safety data sheets include H362 (may cause harm to breast‑fed children) and list lactation effects; clinical drug labels state estrogens are present in human milk and may reduce milk production and are contraindicated or advised against during breastfeeding. Estradiol is systemically bioactive and transfers into milk; topical/transdermal absorption can produce systemic levels. (ECHA/SDS; DailyMed; pharmacology literature).
- estradiol é seguro para a pele do bebê?
- Hazard (H360/H362) is intrinsic to the parent hormone and applies to infants: estradiol is a potent estrogen with well‑characterized receptor activity and documented developmental effects in animal and human observational studies. Exposure via product applied to infant skin would be of high concern because estradiol is absorbable transdermally (used clinically as transdermal therapy) and infant skin has higher surface‑area‑to‑weight and immature barrier — exposure rating increased for infant skin. No infant‑safe cosmetic use is supported. (ECHA/SDS; clinical/transdermal product literature; peer‑reviewed studies on maternal estradiol effects).
- Como o VeriMom pontua estradiol?
- O VeriMom pontua estradiol em 0/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a estradiol na gravidez?
- Veja nossa lista curada de alternativas seguras a estradiol com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.