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HIGH RISK

Devo evitar dibutyl phthalate na gravidez? | VeriMom

Dibutyl phthalate (DBP, CAS 84-74-2) has a harmonised CLP classification as H360 (may damage fertility or the unborn child) and is listed in the EU cosmetics Annex II (prohibited), indicating confirmed reproductive hazard; animal studies show male reproductive/developmental effects consistent with anti-androgenic mechanisms. (ECHA harmonised classification and Annex II listing; CIR and peer-reviewed animal literature support mechanism). Sources: https://echa.europa.eu/ (DBP brief/profile and C&L Annex VI harmonised H360), https://echa.europa.eu/cosmetics-prohibited-substances/-/legislationlist/substance/external/100.001.416, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic

ECHA regulatory hazard statements

  • H360DF

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

dibutyl phthalate é seguro durante a gravidez?
Dibutyl phthalate (DBP, CAS 84-74-2) has a harmonised CLP classification as H360 (may damage fertility or the unborn child) and is listed in the EU cosmetics Annex II (prohibited), indicating confirmed reproductive hazard; animal studies show male reproductive/developmental effects consistent with anti-androgenic mechanisms. (ECHA harmonised classification and Annex II listing; CIR and peer-reviewed animal literature support mechanism). Sources: https://echa.europa.eu/ (DBP brief/profile and C&L Annex VI harmonised H360), https://echa.europa.eu/cosmetics-prohibited-substances/-/legislationlist/substance/external/100.001.416, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic
dibutyl phthalate é seguro durante a amamentação?
Because DBP is a harmonised H360 substance (reproductive toxicant) and has demonstrated endocrine/anti-androgenic effects in animals, it is scored high for hazard and mechanism. DBP is lipophilic and human biomonitoring/authoritative assessments indicate systemic uptake and potential for body burden (supporting possible transfer to breastmilk), so exposure via systemic routes during lactation is rated higher than negligible. Sources: https://echa.europa.eu/brief-profile/-/briefprofile/100.001.416, https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/risk-evaluation-dibutyl-phthalate-12-benzene, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic
dibutyl phthalate é seguro para a pele do bebê?
Harmonised H360 applies irrespective of age (so hazard = 3). Mechanistic data (anti-androgenic/reprotoxic) are demonstrated in vivo in animals and remain relevant. For infant skin exposure, exposure score is increased by +1 relative to adult topical use because infants have higher surface-area-to-weight and more permeable skin and DBP is measurable/systemically absorbable; therefore exposure is moderate. Sources: https://echa.europa.eu/cosmetics-prohibited-substances/-/legislationlist/substance/external/100.001.416, https://echa.europa.eu/brief-profile/-/briefprofile/100.001.416, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic
Como o VeriMom pontua dibutyl phthalate?
O VeriMom pontua dibutyl phthalate em 13/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
Quais são as alternativas seguras a dibutyl phthalate na gravidez?
Veja nossa lista curada de alternativas seguras a dibutyl phthalate com base em função semelhante e classificação sem riscos conhecidos.

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Aviso Médico

Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.

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