VeriMomDevo evitar clotrimazole na gravidez? | VeriMom
Clotrimazole is listed with a harmonised CLP classification of H361 (suspected of damaging fertility or the unborn child) on ECHA, which supports a ‘suspected’ reproductive hazard (h=2). A recent peer‑reviewed rat study showed that systemic exposure to clotrimazole altered maternal and fetal steroid hormone profiles via CYP/steroidogenesis inhibition (demonstrated mechanism → m=2). For typical topical/vaginal cosmetic/OTC use systemic absorption is minimal but measurable, so exposure from topical cosmetic use is rated low (e=1). Sources: ECHA harmonised classification and PubMed study, plus product labeling on animal effects.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- clotrimazole é seguro durante a gravidez?
- Clotrimazole is listed with a harmonised CLP classification of H361 (suspected of damaging fertility or the unborn child) on ECHA, which supports a ‘suspected’ reproductive hazard (h=2). A recent peer‑reviewed rat study showed that systemic exposure to clotrimazole altered maternal and fetal steroid hormone profiles via CYP/steroidogenesis inhibition (demonstrated mechanism → m=2). For typical topical/vaginal cosmetic/OTC use systemic absorption is minimal but measurable, so exposure from topical cosmetic use is rated low (e=1). Sources: ECHA harmonised classification and PubMed study, plus product labeling on animal effects.
- clotrimazole é seguro durante a amamentação?
- Harmonised H361 classification and animal data (CYP inhibition and steroid changes) provide evidence for a suspected reproductive/developmental hazard (h=2) and a demonstrated mechanistic effect (m=2). Topical use shows minimal but measurable systemic absorption and is therefore given low exposure (e=1); breastfeeding guidance notes limited systemic exposure with topical use but advises use only if benefits outweigh risks in some labels.
- clotrimazole é seguro para a pele do bebê?
- Hazard (h=2) remains based on harmonised H361 and animal evidence; mechanism (m=2) is the same (CYP/steroidogenesis effects demonstrated in animals). Exposure is increased by one band for infants because infant skin has higher absorption — adult topical e=1 → baby e=2 (measurable/moderate exposure potential for 0–3 yr). There is limited infant‑specific reproductive/toxicity data; topical clotrimazole has been used in infants in clinical studies but systemic safety data are limited.
- Como o VeriMom pontua clotrimazole?
- O VeriMom pontua clotrimazole em 20/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a clotrimazole na gravidez?
- Veja nossa lista curada de alternativas seguras a clotrimazole com base em função semelhante e classificação sem riscos conhecidos.
Verifique qualquer rótulo em 2 segundos
Baixe o VeriMom grátis — escaneie qualquer produto e veja a pontuação de segurança na gravidez instantaneamente.
Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.