VeriMomDevo evitar cis-retinoic acid na gravidez? | VeriMom
13‑cis‑retinoic acid (isotretinoin, CAS 4759‑48‑2) is a well‑established human teratogen when given systemically (oral isotretinoin causes severe, characteristic birth defects) and is regulated as a pregnancy‑contraindicated retinoid; the teratogenic mechanism is well characterized via retinoic‑acid / retinoid receptor signalling. Topical use gives lower systemic exposure than oral dosing but measurable absorption has been reported for topical retinoids and regulatory guidance treats retinoic acid/isotretinoin as a pregnancy risk. ([fda.gov](https://www.fda.gov/media/166611/download?utm_source=openai))
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FAQ
- cis-retinoic acid é seguro durante a gravidez?
- 13‑cis‑retinoic acid (isotretinoin, CAS 4759‑48‑2) is a well‑established human teratogen when given systemically (oral isotretinoin causes severe, characteristic birth defects) and is regulated as a pregnancy‑contraindicated retinoid; the teratogenic mechanism is well characterized via retinoic‑acid / retinoid receptor signalling. Topical use gives lower systemic exposure than oral dosing but measurable absorption has been reported for topical retinoids and regulatory guidance treats retinoic acid/isotretinoin as a pregnancy risk. ([fda.gov](https://www.fda.gov/media/166611/download?utm_source=openai))
- cis-retinoic acid é seguro durante a amamentação?
- Oral isotretinoin is contraindicated in breastfeeding because of concern for systemic exposure to the infant; the biological mechanism (retinoid receptor activity) is the same as for pregnancy. For topical cosmetic use, systemic transfer into milk is expected to be low but not zero, so breastfeeding exposure is considered low but not negligible. ([fda.gov](https://www.fda.gov/media/166611/download?utm_source=openai))
- cis-retinoic acid é seguro para a pele do bebê?
- There is no infant‑specific evidence that topical cis‑retinoic acid applied to baby skin produces developmental/teratogenic effects (do not upgrade h/m without direct data). However infant skin has higher absorption (immature barrier and higher surface‑area‑to‑weight), so exposure scoring is increased relative to adults if the ingredient is present or applied directly. Topical retinoids are generally discouraged on young children because of irritancy and potential systemic uptake. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/32643315/?utm_source=openai))
- Como o VeriMom pontua cis-retinoic acid?
- O VeriMom pontua cis-retinoic acid em 7/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a cis-retinoic acid na gravidez?
- Veja nossa lista curada de alternativas seguras a cis-retinoic acid com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.