VeriMomDevo evitar captan na gravidez? | VeriMom
Captan has been flagged as a suspected reproductive hazard (H361-level concern reported in regulatory dossiers and SDSs) and animal/experimental studies report effects on reproductive tissues (mouse ovarian disruption, decreased fertility in some rodent studies). Mechanistic studies show mitochondrial dysfunction, oxidative stress, DNA damage and apoptosis in oocytes (demonstrated in vivo/in vitro). For topical/cosmetic use dermal absorption is reported to be very low (<1% per hour in regulatory assessments and human toxicokinetic studies), so exposure from cosmetic topical use is low but measurable. Sources: PubMed (mouse ovarian study), EPA/NPIC summaries, human toxicokinetic/dermal studies and occupational assessments.
ECHA regulatory hazard statements
- •H351
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- captan é seguro durante a gravidez?
- Captan has been flagged as a suspected reproductive hazard (H361-level concern reported in regulatory dossiers and SDSs) and animal/experimental studies report effects on reproductive tissues (mouse ovarian disruption, decreased fertility in some rodent studies). Mechanistic studies show mitochondrial dysfunction, oxidative stress, DNA damage and apoptosis in oocytes (demonstrated in vivo/in vitro). For topical/cosmetic use dermal absorption is reported to be very low (<1% per hour in regulatory assessments and human toxicokinetic studies), so exposure from cosmetic topical use is low but measurable. Sources: PubMed (mouse ovarian study), EPA/NPIC summaries, human toxicokinetic/dermal studies and occupational assessments.
- captan é seguro durante a amamentação?
- Hazard and mechanism same rationale as for pregnancy (animal reproductive effects and mechanistic evidence). Dermal absorption from topical application is low (human toxicokinetic data and EPA/NPIC assessments), and while captan metabolites have been detected in animal milk in some studies, human milk transfer data are sparse — exposure via maternal topical use is therefore low but measurable. Sources: NPIC/EPA summaries, human dermal toxicokinetic study, animal milk data.
- captan é seguro para a pele do bebê?
- Hazard (H361-level/suspected reproductive/developmental effects) and mechanistic findings apply (animal reproductive/ovarian effects, demonstrated oocyte toxicity). Dermal absorption for adults is low but measurable; per your scoring rules, infant skin exposure is increased by +1 because infant skin has higher permeability and higher surface-area-to-weight, so exposure for a baby (0–3 yr) is moderate. There is no infant-specific evidence to raise hazard or mechanism scores beyond the adult evidence. Sources: human dermal/tokinetic studies, EPA/NPIC, PubMed reproductive/toxicology studies.
- Como o VeriMom pontua captan?
- O VeriMom pontua captan em 20/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a captan na gravidez?
- Veja nossa lista curada de alternativas seguras a captan com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.