VeriMomDevo evitar basic yellow 57 na gravidez? | VeriMom
Animal developmental studies report fetal malformations at very high oral doses (developmental NOAEL corrected ≈237 mg/kg bw/day; adverse effects at 1000 mg/kg in rats), supporting suspected developmental hazard based on animal data. The ingredient does not have a harmonised H360 classification, but animal reproductive/developmental findings justify h=2 (suspected). Dermal absorption from representative cosmetic formulations is low but measurable in in vitro pig skin studies (2–4% bioavailable after 48 h) and reported cosmetic uses are primarily hair dyes at low concentrations, so exposure from normal topical cosmetic use is low but non‑negligible. (CIR safety assessment; SCCS summary; ECHA substance record).
ECHA regulatory hazard statements
- •H361D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- basic yellow 57 é seguro durante a gravidez?
- Animal developmental studies report fetal malformations at very high oral doses (developmental NOAEL corrected ≈237 mg/kg bw/day; adverse effects at 1000 mg/kg in rats), supporting suspected developmental hazard based on animal data. The ingredient does not have a harmonised H360 classification, but animal reproductive/developmental findings justify h=2 (suspected). Dermal absorption from representative cosmetic formulations is low but measurable in in vitro pig skin studies (2–4% bioavailable after 48 h) and reported cosmetic uses are primarily hair dyes at low concentrations, so exposure from normal topical cosmetic use is low but non‑negligible. (CIR safety assessment; SCCS summary; ECHA substance record).
- basic yellow 57 é seguro durante a amamentação?
- No human lactation studies were located. Animal developmental/reprotoxic findings indicate a suspected hazard (h=2). There is no evidence of a specific reproductive mechanism or documented transfer into milk; dermal systemic absorption from cosmetic use is low but measurable so maternal systemic exposure (and therefore potential, but likely low, transfer into breastmilk) is possible. (CIR; ECHA).
- basic yellow 57 é seguro para a pele do bebê?
- Hazard score follows the animal developmental data (h=2). Mechanistic data for developmental/ endocrine modes of action were not identified (m=0). Measurable dermal bioavailability in in vitro skin studies (2–4% over 48 h) means exposure on infant skin is higher relative to adults due to immature barrier and higher surface‑area‑to‑weight; per scoring rules increase exposure by +1 giving e=2 for 0–3 y infants. No infant‑specific absorption studies were found. (CIR dermal absorption data; SCCS/CIR use‑levels).
- Como o VeriMom pontua basic yellow 57?
- O VeriMom pontua basic yellow 57 em 33/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a basic yellow 57 na gravidez?
- Veja nossa lista curada de alternativas seguras a basic yellow 57 com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.