Devo evitar basic blue 9 na gravidez? | VeriMom
Methylene blue (Basic Blue 9, CAS 61-73-4) is associated with documented fetal harm after intra‑amniotic exposure (case series of jejuno‑ileal/intestinal atresia and fetal death); regulatory/clinical sources note teratogenic risk and recommend avoiding intra‑amniotic use in pregnancy. ECHA record references a harmonised/suspected reproduction hazard (H361) for this substance, and clinical teratology reviews/monographs (UKTIS, StatPearls, PubMed case reports) describe the fetal risks. Topical cosmetic use would give low but measurable systemic exposure only, so pregnancy exposure from normal topical use is judged low but not zero. (Sources: ECHA substance info; UKTIS monograph; PubMed case reports; StatPearls.)
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- basic blue 9 é seguro durante a gravidez?
- Methylene blue (Basic Blue 9, CAS 61-73-4) is associated with documented fetal harm after intra‑amniotic exposure (case series of jejuno‑ileal/intestinal atresia and fetal death); regulatory/clinical sources note teratogenic risk and recommend avoiding intra‑amniotic use in pregnancy. ECHA record references a harmonised/suspected reproduction hazard (H361) for this substance, and clinical teratology reviews/monographs (UKTIS, StatPearls, PubMed case reports) describe the fetal risks. Topical cosmetic use would give low but measurable systemic exposure only, so pregnancy exposure from normal topical use is judged low but not zero. (Sources: ECHA substance info; UKTIS monograph; PubMed case reports; StatPearls.)
- basic blue 9 é seguro durante a amamentação?
- There are no strong human data specifically about transfer into breast milk, but given systemic use can produce fetal/ neonatal effects and that methylene blue is systemically active, a conservative rating is maintained (suspected reproductive hazard). Clinical guidance cautions use in pregnancy; breastfeeding exposure potential is unknown but systemic maternal exposure could result in transfer—therefore exposure from typical topical cosmetic use is likely low but measurable. (Sources: UKTIS, StatPearls, PubMed case literature.)
- basic blue 9 é seguro para a pele do bebê?
- Infant-specific evidence of increased sensitivity is lacking; however because the ingredient has measurable absorption in humans and is systemically active, the exposure score for baby skin is increased by +1 versus adult (immature barrier and higher surface‑area:weight). No infant‑topical studies showing unique teratogenicity were found, so hazard/mechanism scores are not increased beyond the pregnancy assessment. (Sources: PubMed case reports; UKTIS; general toxicology summaries.)
- Como o VeriMom pontua basic blue 9?
- O VeriMom pontua basic blue 9 em 20/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a basic blue 9 na gravidez?
- Veja nossa lista curada de alternativas seguras a basic blue 9 com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.