VeriMomDevo evitar aziridine na gravidez? | VeriMom
Aziridine (ethyleneimine, CAS 151-56-4) has harmonised/regulatory classifications and authoritative toxicology indicating mutagenic and carcinogenic properties (ECHA registration/C&L info, EPA/IRIS, IARC). Harmonised flags for reproductive hazard (suspected; H361 reported in regulatory sources) support 'suspected' reproductive hazard (h=2). The mechanism is well-supported as an alkylating/genotoxic agent (demonstrated genotoxicity/mutagenicity) so m=2. For topical exposure, aziridine is a small, reactive molecule with reported dermal absorption and clear systemic toxicity in occupational/animal data, so exposure from topical use would be at least measurable/moderate (e=2). Sources: ECHA dossier/C&L summaries, EPA IRIS/FACT sheet, NIOSH/NIH toxicology summaries, IARC summary.
ECHA regulatory hazard statements
- •H350
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- aziridine é seguro durante a gravidez?
- Aziridine (ethyleneimine, CAS 151-56-4) has harmonised/regulatory classifications and authoritative toxicology indicating mutagenic and carcinogenic properties (ECHA registration/C&L info, EPA/IRIS, IARC). Harmonised flags for reproductive hazard (suspected; H361 reported in regulatory sources) support 'suspected' reproductive hazard (h=2). The mechanism is well-supported as an alkylating/genotoxic agent (demonstrated genotoxicity/mutagenicity) so m=2. For topical exposure, aziridine is a small, reactive molecule with reported dermal absorption and clear systemic toxicity in occupational/animal data, so exposure from topical use would be at least measurable/moderate (e=2). Sources: ECHA dossier/C&L summaries, EPA IRIS/FACT sheet, NIOSH/NIH toxicology summaries, IARC summary.
- aziridine é seguro durante a amamentação?
- Same hazard and mechanism rationale as pregnancy (suspected reproductive/teratogenic risk via genotoxic/alkylating activity). No specific human lactation transfer data located, but systemic toxicity and dermal absorption reported in authoritative sources imply measurable maternal exposure and potential for transfer into breastmilk (therefore e=2).
- aziridine é seguro para a pele do bebê?
- Hazard and mechanism as above (h=2, m=2). Because infant skin (0–3 yr) has higher surface-area-to-weight and an immature barrier, exposure score increases by +1 relative to adult topical exposure (adult e=2 → baby e=3). There is no infant-specific toxicokinetic evidence to change hazard or mechanism scores, only exposure.
- Como o VeriMom pontua aziridine?
- O VeriMom pontua aziridine em 13/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a aziridine na gravidez?
- Veja nossa lista curada de alternativas seguras a aziridine com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.