VeriMomDevo evitar acrolein na gravidez? | VeriMom
Acrolein (CAS 107-02-8) is a reactive α,β‑unsaturated aldehyde with animal data showing reproductive/developmental effects (reduced pup weights, effects on fetal/testicular endpoints) in rodents at systemic/toxic doses; therefore it is a suspected reproductive hazard based on animal evidence. Mechanistic studies demonstrate mitochondrial/glycolytic disruption and oocyte/embryo toxicity in vitro and in vivo, supporting a demonstrated mechanism. Topical/cosmetic exposure would generally give low but measurable systemic exposure if present because acrolein is small and reactive, but routine cosmetic formulations do not commonly include free acrolein; therefore exposure from intended cosmetic topical use is judged low.
ECHA regulatory hazard statements
- •H225
- •H330
- •H311
- •H300
- •H314
- •H400
- •H410
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- acrolein é seguro durante a gravidez?
- Acrolein (CAS 107-02-8) is a reactive α,β‑unsaturated aldehyde with animal data showing reproductive/developmental effects (reduced pup weights, effects on fetal/testicular endpoints) in rodents at systemic/toxic doses; therefore it is a suspected reproductive hazard based on animal evidence. Mechanistic studies demonstrate mitochondrial/glycolytic disruption and oocyte/embryo toxicity in vitro and in vivo, supporting a demonstrated mechanism. Topical/cosmetic exposure would generally give low but measurable systemic exposure if present because acrolein is small and reactive, but routine cosmetic formulations do not commonly include free acrolein; therefore exposure from intended cosmetic topical use is judged low.
- acrolein é seguro durante a amamentação?
- Same hazard and mechanism considerations apply for lactation: animal reproductive/developmental effects and mechanistic evidence indicate a suspected reproductive hazard. For cosmetic topical use systemic absorption is expected to be low but measurable, so transfer into breastmilk could theoretically occur if significant systemic levels were reached, but typical cosmetic exposures are low.
- acrolein é seguro para a pele do bebê?
- Hazard and mechanism same as for adults (suspected reproductive/developmental hazard with demonstrated mitochondrial/oocyte effects). Exposure score is increased by +1 for infants (per your rule) because acrolein has measurable dermal effects (it is skin‑corrosive/irritant and a small reactive molecule) so infants’ higher surface‑area‑to‑weight and immature barrier raise likely systemic uptake from topical application above adult levels.
- Como o VeriMom pontua acrolein?
- O VeriMom pontua acrolein em 20/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a acrolein na gravidez?
- Veja nossa lista curada de alternativas seguras a acrolein com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.