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HIGH RISK

Devo evitar acetanilid na gravidez? | VeriMom

Animal reproductive/developmental studies (OECD SIDS / repeated-dose and reproduction studies) report reproductive/developmental effects and NOAELs in rats; several manufacturer SDS also list H361 (suspected of damaging fertility or the unborn child), so acetanilide is reasonably suspected from animal data. Mechanistic data are limited — metabolism to aniline/phenolic metabolites is known (theoretical concern) but there is no well-characterised placental-transfer or endocrine-disruption mechanism for acetanilide in humans. Topical cosmetic absorption is expected to be low but measurable (low log Kow, used at low concentrations), so exposure from typical topical use is low but non‑zero.

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

acetanilid é seguro durante a gravidez?
Animal reproductive/developmental studies (OECD SIDS / repeated-dose and reproduction studies) report reproductive/developmental effects and NOAELs in rats; several manufacturer SDS also list H361 (suspected of damaging fertility or the unborn child), so acetanilide is reasonably suspected from animal data. Mechanistic data are limited — metabolism to aniline/phenolic metabolites is known (theoretical concern) but there is no well-characterised placental-transfer or endocrine-disruption mechanism for acetanilide in humans. Topical cosmetic absorption is expected to be low but measurable (low log Kow, used at low concentrations), so exposure from typical topical use is low but non‑zero.
acetanilid é seguro durante a amamentação?
Same animal evidence that supports a suspected reproductive/developmental hazard applies to lactation context (no human breastfeeding-specific safety data). Mechanistic concerns are theoretical (metabolism to aniline); topical absorption is likely low but measurable so maternal systemic exposure from cosmetics could be low but not zero, with potential for transfer into milk not well studied.
acetanilid é seguro para a pele do bebê?
Hazard scoring follows the animal evidence (suspected reproductive/developmental hazard). Mechanistic evidence remains theoretical. Exposure score increased by +1 for infants (per instructions) because baby skin has higher surface-area-to-weight and an immature barrier and acetanilide has measurable (though limited) dermal absorption; thus infant exposure from topical products is moderate rather than low.
Como o VeriMom pontua acetanilid?
O VeriMom pontua acetanilid em 27/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
Quais são as alternativas seguras a acetanilid na gravidez?
Veja nossa lista curada de alternativas seguras a acetanilid com base em função semelhante e classificação sem riscos conhecidos.

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Aviso Médico

Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.

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