Devo evitar 5-bromo-5-nitro-1,3-dioxane na gravidez? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

5-bromo-5-nitro-1,3-dioxane é seguro durante a gravidez?

Authoritative cosmetic reviews (CIR references) and regulatory reviews do not report convincing reproductive or teratogenic effects for 5-bromo-5-nitro-1,3-dioxane (bronidox); some sources report negative Ames tests and no clear repro/mutagenicity in the limited data available. Although some C&L notifications list H361 (suspected of damaging fertility or the unborn child), I could not find a harmonised Annex VI (legal) classification for this CAS — notifications/self-classifications alone do not raise the hazard score under your rules. Exposure from intended cosmetic topical use is low (used as a cosmetic preservative at up to ~0.1%, mainly in rinse-off products), so I scored exposure as 1 (low but measurable). Sources: CIR/regulatory reviews and ECHA registration/brief profile and reports cited below.

5-bromo-5-nitro-1,3-dioxane é seguro durante a amamentação?

No specific data were found showing reproductive or lactation-specific toxicity or transfer into breast milk. Mechanistic or experimental evidence of breast‑milk transfer is absent in the reviewed sources; therefore hazard and mechanism are scored 0 and exposure is scored 1 (low but measurable) for typical cosmetic topical use. See sources below for preservative use, regulatory restrictions and toxicology summaries.

5-bromo-5-nitro-1,3-dioxane é seguro para a pele do bebê?

There is no infant-specific reproductive or developmental toxicity evidence. However, because bronidox is a small preservative used topically (and is reported to be skin‑irritating / a sensitizer at higher concentrations) I increased exposure by +1 for infants (immature barrier and higher surface-area-to-weight); this gives e=2. There is no infant-specific data to justify increasing hazard (h) or mechanism (m). Also note regulatory guidance restricts use to rinse‑off products and maximum concentrations (see sources).

Como o VeriMom pontua 5-bromo-5-nitro-1,3-dioxane?

O VeriMom pontua 5-bromo-5-nitro-1,3-dioxane em 33/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.

Quais são as alternativas seguras a 5-bromo-5-nitro-1,3-dioxane na gravidez?

Veja nossa lista curada de alternativas seguras a 5-bromo-5-nitro-1,3-dioxane com base em função semelhante e classificação sem riscos conhecidos.