VeriMomDevo evitar 2-hydroxyethyl picramic acid na gravidez? | VeriMom
ECHA lists a harmonised CLP classification for 2-hydroxyethyl picramic acid (Index No. 604-056-00-2, CAS 99610-72-7) including H361f (suspected of damaging fertility), which per EU harmonised CLP guidance is a Category 2 reproductive hazard (supports h=2). Peer-review/regulatory assessments (SCCS/CIR/IMAP/TGA summaries) report animal data and testicular effects, indicating a demonstrated reproductive mechanism (m=2). Topical exposure from hair-dye use is low but measurable (SCCS evaluated on-head limits such as 0.6% and concluded risk mainly from sensitisation), so exposure for pregnant adults from cosmetic use is assessed as low but measurable (e=1).
ECHA regulatory hazard statements
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- 2-hydroxyethyl picramic acid é seguro durante a gravidez?
- ECHA lists a harmonised CLP classification for 2-hydroxyethyl picramic acid (Index No. 604-056-00-2, CAS 99610-72-7) including H361f (suspected of damaging fertility), which per EU harmonised CLP guidance is a Category 2 reproductive hazard (supports h=2). Peer-review/regulatory assessments (SCCS/CIR/IMAP/TGA summaries) report animal data and testicular effects, indicating a demonstrated reproductive mechanism (m=2). Topical exposure from hair-dye use is low but measurable (SCCS evaluated on-head limits such as 0.6% and concluded risk mainly from sensitisation), so exposure for pregnant adults from cosmetic use is assessed as low but measurable (e=1).
- 2-hydroxyethyl picramic acid é seguro durante a amamentação?
- Harmonised CLP H361f applies; regulatory reviews cite reproductive toxicity in animals (m=2) and harmonised classification carries to concerns for breastfeeding parents. Topical cosmetic use gives low but measurable exposure (SCCS on-head limits), so e=1 for lactating adults. There are no specific data showing transfer into breastmilk identified in the reviewed sources (data gap).
- 2-hydroxyethyl picramic acid é seguro para a pele do bebê?
- Hazard (H361f harmonised) and reported animal reproductive/testicular effects justify h=2 for infant-related concern under the requested scoring system. Mechanistic evidence from animal reproductive toxicology supports m=2. Because infant skin (0–3 yr) has a higher surface‑area:weight and an immature barrier, exposure score is increased by +1 relative to adults (adult e=1 → infant e=2) where topically applied products or accidental exposure could occur. No infant-specific absorption studies were found. (See data gaps.)
- Como o VeriMom pontua 2-hydroxyethyl picramic acid?
- O VeriMom pontua 2-hydroxyethyl picramic acid em 20/100 (risco alto) com base no status EU CosIng, classificações de perigo ECHA e estudos revisados por pares no PubMed. Nosso pipeline de pontuação é totalmente transparente.
- Quais são as alternativas seguras a 2-hydroxyethyl picramic acid na gravidez?
- Veja nossa lista curada de alternativas seguras a 2-hydroxyethyl picramic acid com base em função semelhante e classificação sem riscos conhecidos.
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Aviso Médico
Estas informações são apenas para fins educacionais e não constituem aconselhamento médico. As pontuações de segurança são baseadas em dados publicamente disponíveis e podem não refletir todos os riscos. Sempre consulte seu profissional de saúde antes de usar qualquer produto durante a gravidez ou amamentação.