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vitex agnus castus extract은 임신 중 안전한가요?

Multiple regulatory reviews and clinical reviews recommend avoiding Vitex agnus‑castus during pregnancy because the botanical has demonstrated effects on reproductive hormones (prolactin/progestogenic activity) and at least one animal study reported adverse pregnancy outcomes, so it is classed as 'suspected' reproductive hazard rather than confirmed harmonised CMR. (see TGA/EMA guidance; systematic review and PubMed animal study). Sources: TGA safety notice; systematic review/DARE; rat study. https://www.tga.gov.au/safety/safety-monitoring-and-information/safety-alerts/vitex-agnus-castus, https://www.ncbi.nlm.nih.gov/books/NBK71283/, https://pubmed.ncbi.nlm.nih.gov/35837144/

성분
vitex agnus castus extract
중간 위험
40
/100
0

Pregnancy-safe products containing vitex agnus castus extract

임신 중 vitex agnus castus extract 대체 안전 성분 | VeriMom

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vitex agnus castus extract은 임신 중 안전한가요?
Multiple regulatory reviews and clinical reviews recommend avoiding Vitex agnus‑castus during pregnancy because the botanical has demonstrated effects on reproductive hormones (prolactin/progestogenic activity) and at least one animal study reported adverse pregnancy outcomes, so it is classed as 'suspected' reproductive hazard rather than confirmed harmonised CMR. (see TGA/EMA guidance; systematic review and PubMed animal study). Sources: TGA safety notice; systematic review/DARE; rat study. https://www.tga.gov.au/safety/safety-monitoring-and-information/safety-alerts/vitex-agnus-castus, https://www.ncbi.nlm.nih.gov/books/NBK71283/, https://pubmed.ncbi.nlm.nih.gov/35837144/
vitex agnus castus extract은 모유 수유 중 안전한가요?
Authoritative breastfeeding resources and reviews (LactMed / safety reviews) advise avoiding Vitex in lactation because it alters prolactin and may affect milk production and infant hormone exposure; this demonstrates a mechanistic concern (endocrine activity) and justifies a 'suspected' hazard score. Dermal/topical cosmetic use gives low systemic exposure but transfer into breastmilk is plausible with systemic administration; topical exposure is likely lower. Sources: LactMed (Chasteberry), systematic reviews, regulatory advisories. https://www.ncbi.nlm.nih.gov/books/NBK501807/, https://www.ncbi.nlm.nih.gov/books/NBK71283/
vitex agnus castus extract은 아기 피부에 안전한가요?
No direct evidence shows teratogenicity or infant‑skin specific reproductive toxicity from topical Vitex extracts, but the ingredient contains hormone‑active constituents (flavonoids, diterpenoids) which create a theoretical/class‑based concern for infants (hence h=1, m=1). Because infant skin has higher permeability, exposure score is increased by +1 relative to adult topical use (adult e=1 → infant e=2). Sources: phytochemistry summaries and reviews; translational guidance on avoiding systemic hormone modulators for infants. https://en.wikipedia.org/wiki/Vitex_agnus-castus, https://phcogrev.com/article/2018/12/23/104103phrevphrev2217
VeriMom은 vitex agnus castus extract을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 vitex agnus castus extract을 40/100 (중간 위험)로 평가합니다.
임신 중 vitex agnus castus extract 대체 안전 성분은?
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