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tromethamine은 임신 중 안전한가요?

Animal reproductive/developmental studies reported increased embryo resorptions (300 mg/kg/day) and complete litter resorption at a high dose in rats, which supports a suspected reproductive hazard at high systemic doses. The CIR review nevertheless concluded tromethamine is safe in current cosmetic uses (up to ~4% in leave‑on products), indicating cosmetic topical exposures are much lower than doses causing effects in animals. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/Tromet_faa-final.pdf))

성분
tromethamine
중간 위험
47
/100
0

Pregnancy-safe products containing tromethamine

임신 중 tromethamine 대체 안전 성분 | VeriMom

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Frequently asked questions

tromethamine은 임신 중 안전한가요?
Animal reproductive/developmental studies reported increased embryo resorptions (300 mg/kg/day) and complete litter resorption at a high dose in rats, which supports a suspected reproductive hazard at high systemic doses. The CIR review nevertheless concluded tromethamine is safe in current cosmetic uses (up to ~4% in leave‑on products), indicating cosmetic topical exposures are much lower than doses causing effects in animals. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/Tromet_faa-final.pdf))
tromethamine은 모유 수유 중 안전한가요?
Because animal data show reproductive/developmental effects at high systemic doses, a suspected hazard for nursing infants is plausible if maternal systemic exposure were similar; however CIR and product-use data indicate topical cosmetic use yields low systemic exposure, making milk transfer unlikely at consumer exposures. There are no human lactation/breastmilk transfer data identified in the reviewed sources. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/Tromet_faa-final.pdf))
tromethamine은 아기 피부에 안전한가요?
Hazard (animal reproductive effects) remains the same (suspected) absent infant‑specific developmental toxicity data, but exposure via baby skin is increased relative to adults because of higher surface‑area‑to‑weight and immature barrier — cosmetic dermal absorption is low but measurable so exposure score is increased by +1 for infants. CIR usage data show cosmetic concentrations and irritation/pH effects are the primary topical concerns rather than systemic toxicity at typical use. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/Tromet_faa-final.pdf))
VeriMom은 tromethamine을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 tromethamine을 47/100 (중간 위험)로 평가합니다.
임신 중 tromethamine 대체 안전 성분은?
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