trichosanthes kirilowii root extract은 임신 중 안전한가요?

임신 중 trichosanthes kirilowii root extract 대체 안전 성분 | VeriMom

Related ingredients

Frequently asked questions

trichosanthes kirilowii root extract은 임신 중 안전한가요?

Animal and mechanistic data show trichosanthin (from T. kirilowii root) is embryotoxic/abortifacient and has been used clinically to induce abortion, so reproductive hazard is supported (h=2). The mechanism is demonstrated (ribosome‑inactivating protein with demonstrated abortion mechanisms in experimental studies), so m=2. For topical cosmetic use exposure is likely low but measurable (e=1) because extracts are applied topically and some dermal uptake or local activity is possible depending on formulation; however systemic exposure from typical cosmetic topical use is likely limited. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8102209/?utm_source=openai))

trichosanthes kirilowii root extract은 모유 수유 중 안전한가요?

Because the same demonstrable reproductive/embryotoxic hazard exists for trichosanthin and systemic exposure (even small) could theoretically transfer into breastmilk, breastfeeding is flagged at the same hazard and mechanism level (h=2, m=2). Expected dermal/topical exposure is low but measurable (e=1); no direct data on lactational transfer from topical cosmetic use were found. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8102209/?utm_source=openai))

trichosanthes kirilowii root extract은 아기 피부에 안전한가요?

Hazard and mechanism are unchanged for infant skin (h=2, m=2) because the same toxic constituent (trichosanthin) is responsible. Exposure score is increased by +1 for baby skin to e=2 because infant skin has a higher surface‑area‑to‑weight ratio and less mature barrier, making dermal absorption and systemic exposure more likely from topical application of products containing the extract. No infant‑specific safety studies for topical T. kirilowii root extract were located. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8102209/?utm_source=openai))

VeriMom은 trichosanthes kirilowii root extract을 어떻게 평가하나요?

VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 trichosanthes kirilowii root extract을 40/100 (중간 위험)로 평가합니다.

임신 중 trichosanthes kirilowii root extract 대체 안전 성분은?

유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.