spironolactone은 임신 중 안전한가요?
Spironolactone has a harmonised CLP reproductive toxicity classification (H360 — 'May damage fertility or the unborn child') on ECHA records/annex listings, and animal and case-report data support anti‑androgenic effects on fetal sexual development; mechanism is well characterised (anti‑androgenic activity demonstrated in vivo). Topical cosmetic use would usually give low systemic exposure compared with oral therapeutic dosing, so exposure from typical topical cosmetic use is judged low but measurable. Sources: ECHA CLP/harmonised listing, FDA product label, animal/human reports (PubMed/PMC).
임신 중 spironolactone 대체 안전 성분 | VeriMom
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Frequently asked questions
- spironolactone은 임신 중 안전한가요?
- Spironolactone has a harmonised CLP reproductive toxicity classification (H360 — 'May damage fertility or the unborn child') on ECHA records/annex listings, and animal and case-report data support anti‑androgenic effects on fetal sexual development; mechanism is well characterised (anti‑androgenic activity demonstrated in vivo). Topical cosmetic use would usually give low systemic exposure compared with oral therapeutic dosing, so exposure from typical topical cosmetic use is judged low but measurable. Sources: ECHA CLP/harmonised listing, FDA product label, animal/human reports (PubMed/PMC).
- spironolactone은 모유 수유 중 안전한가요?
- Intrinsic hazard remains at H360 level (may damage the unborn child/fertility). Mechanism (anti‑androgenic activity / endocrine effects) is well characterised. Clinical/lactation databases (LactMed, NHS) report low transfer of spironolactone into breast milk and no consistent adverse effects in reported infants at therapeutic maternal doses, so exposure to a breastfed infant from maternal systemic dosing is generally low; for cosmetic topical use systemic levels would be expected to be lower still (low but potentially measurable).
- spironolactone은 아기 피부에 안전한가요?
- The substance carries harmonised H360 (intrinsic reproductive hazard) so hazard score is 3. Mechanistic anti‑androgenic activity is well characterised. Exposure for infants (0–3 yr) is higher than adults for a given topical exposure because of immature barrier and higher surface‑area‑to‑weight; therefore exposure score is increased by one compared with adult topical use (adult topical e=1 → infant e=2). There is no infant‑specific evidence to change hazard or mechanism scores.
- VeriMom은 spironolactone을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 spironolactone을 13/100 (높은 위험)로 평가합니다.
- 임신 중 spironolactone 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.