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pueraria lobata root extract은 임신 중 안전한가요?

Pueraria lobata root extract contains isoflavones (notably puerarin, daidzein, genistein) that show estrogenic activity in vitro and have produced reproductive/anti‑implantation effects in animal studies (rats). These animal reproductive findings justify a 'suspected' reproductive hazard (h=2) and indicate a demonstrated endocrine mechanism (m=2). Dermal exposure from cosmetics is expected to be low but measurable (e=1). Sources: Reproduction (puerarin disrupts pregnancy in rats) and in vitro estrogenic studies. (see sources).

성분
pueraria lobata root extract
중간 위험
40
/100
0

임신 중 pueraria lobata root extract 대체 안전 성분 | VeriMom

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pueraria lobata root extract은 임신 중 안전한가요?
Pueraria lobata root extract contains isoflavones (notably puerarin, daidzein, genistein) that show estrogenic activity in vitro and have produced reproductive/anti‑implantation effects in animal studies (rats). These animal reproductive findings justify a 'suspected' reproductive hazard (h=2) and indicate a demonstrated endocrine mechanism (m=2). Dermal exposure from cosmetics is expected to be low but measurable (e=1). Sources: Reproduction (puerarin disrupts pregnancy in rats) and in vitro estrogenic studies. (see sources).
pueraria lobata root extract은 모유 수유 중 안전한가요?
Same hazard and mechanism apply for lactating people because the active constituents are phytoestrogens with demonstrated endocrine activity in animals/in vitro. Topical application to the breast would give low but measurable exposure to the parent; systemic transfer into milk is plausible for small lipophilic isoflavones but direct human lactation data are lacking, so exposure is rated low (e=1). Animal reproductive/lactation-specific data are limited. See cited animal and in vitro studies.
pueraria lobata root extract은 아기 피부에 안전한가요?
Hazard and mechanism remain 'suspected' (h=2/m=2) because the extract contains phytoestrogens shown to have reproductive effects in animals and estrogenic activity in vitro. Absorption concern is increased for infants (immature skin barrier and higher surface‑area‑to‑weight); therefore exposure is increased by +1 to e=2 even though absolute dermal absorption data for the extract are limited. No infant‑specific toxicity studies were identified.
VeriMom은 pueraria lobata root extract을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 pueraria lobata root extract을 40/100 (중간 위험)로 평가합니다.
임신 중 pueraria lobata root extract 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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