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polygonum cuspidatum root extract은 임신 중 안전한가요?

Polygonum cuspidatum root extract is a botanical source of resveratrol (and related stilbenes). Resveratrol is a phytoestrogen with demonstrated estrogen receptor agonist/partial‑agonist activity in vitro and in vivo, giving a class/mechanistic concern (m=2) but there is no EU Annex II ban or confirmed harmonised CLP H360/H350/H340 for the extract — thus hazard is scored as 1. Topical/percutaneous absorption of resveratrol is low-to-measurable, so exposure is scored 1. (Sources: PubMed reviews/studies on resveratrol ER activity; in vitro/in vivo skin permeation studies; CosIng/CIR/Cosmetic lists show extract as a cosmetic ingredient, not banned.)

성분
polygonum cuspidatum root extract
중간 위험
60
/100
0

임신 중 polygonum cuspidatum root extract 대체 안전 성분 | VeriMom

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polygonum cuspidatum root extract은 임신 중 안전한가요?
Polygonum cuspidatum root extract is a botanical source of resveratrol (and related stilbenes). Resveratrol is a phytoestrogen with demonstrated estrogen receptor agonist/partial‑agonist activity in vitro and in vivo, giving a class/mechanistic concern (m=2) but there is no EU Annex II ban or confirmed harmonised CLP H360/H350/H340 for the extract — thus hazard is scored as 1. Topical/percutaneous absorption of resveratrol is low-to-measurable, so exposure is scored 1. (Sources: PubMed reviews/studies on resveratrol ER activity; in vitro/in vivo skin permeation studies; CosIng/CIR/Cosmetic lists show extract as a cosmetic ingredient, not banned.)
polygonum cuspidatum root extract은 모유 수유 중 안전한가요?
Same rationale as pregnancy: phytoestrogenic activity of resveratrol provides a mechanistic concern but no harmonised CMR or EU cosmetic ban; topical exposure is low but measurable. Breastfeeding-specific transfer data for topical resveratrol/extract are lacking, so exposure is treated as low (e=1).
polygonum cuspidatum root extract은 아기 피부에 안전한가요?
Hazard and mechanism same as adults (no infant‑specific evidence to change h or m). Because infants 0–3 yrs have an immature skin barrier and higher surface‑area‑to‑weight, exposure is increased by +1 (adult e=1 → infant e=2) when the ingredient/formulation allows measurable skin absorption (supported by dermal permeation studies for resveratrol).
VeriMom은 polygonum cuspidatum root extract을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 polygonum cuspidatum root extract을 60/100 (중간 위험)로 평가합니다.
임신 중 polygonum cuspidatum root extract 대체 안전 성분은?
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