VeriMompaeonol은 임신 중 안전한가요?
No EU Annex II/III listing or harmonised reproductive (H360/H361) classification was found for paeonol (ECHA substance page). The CIR safety assessment of Paeonia-derived ingredients (which identifies paeonol as a major constituent) did not identify reproductive/developmental hazards and concluded data were insufficient to make safety determinations for most extracts rather than finding a reproductive hazard (CIR, Dec 13, 2024). Limited animal/experimental reports show tissue distribution to uterus after oral dosing in mice but do not demonstrate developmental toxicity (PubMed). Therefore hazard (h) is 0; a low but measurable topical absorption is plausible so exposure (e) is 1. Sources: https://www.cir-safety.org/sites/default/files/TR_PaeoniaSuffruticosa_122024.pdf, https://pubmed.ncbi.nlm.nih.gov/32058234/, https://echa.europa.eu/substance-information/-/substanceinfo/100.008.194
Pregnancy-safe products containing paeonol
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Frequently asked questions
- paeonol은 임신 중 안전한가요?
- No EU Annex II/III listing or harmonised reproductive (H360/H361) classification was found for paeonol (ECHA substance page). The CIR safety assessment of Paeonia-derived ingredients (which identifies paeonol as a major constituent) did not identify reproductive/developmental hazards and concluded data were insufficient to make safety determinations for most extracts rather than finding a reproductive hazard (CIR, Dec 13, 2024). Limited animal/experimental reports show tissue distribution to uterus after oral dosing in mice but do not demonstrate developmental toxicity (PubMed). Therefore hazard (h) is 0; a low but measurable topical absorption is plausible so exposure (e) is 1. Sources: https://www.cir-safety.org/sites/default/files/TR_PaeoniaSuffruticosa_122024.pdf, https://pubmed.ncbi.nlm.nih.gov/32058234/, https://echa.europa.eu/substance-information/-/substanceinfo/100.008.194
- paeonol은 모유 수유 중 안전한가요?
- No data were located indicating paeonol is a known lactation teratogen or has harmonised reproductive/lactation classification (ECHA; CIR). There are reports that whole peony preparations can affect prolactin, but these refer to other peony constituents (paeoniflorin) and not paeonol specifically (LactMed/peony summaries). Given limited systemic exposure from typical topical cosmetic use, exposure via milk is expected to be low but measurable (h=0, e=1). Sources: https://www.cir-safety.org/sites/default/files/TR_PaeoniaSuffruticosa_122024.pdf, https://www.ncbi.nlm.nih.gov/books/NBK501902/, https://echa.europa.eu/substance-information/-/substanceinfo/100.008.194
- paeonol은 아기 피부에 안전한가요?
- No evidence specific to infants (0–3 yr) shows developmental or reproductive hazard for paeonol and no harmonised CMR classification exists (ECHA; CIR). However, because paeonol is a small phenolic molecule used topically and dermal absorption is plausible, infant exposure is higher due to immature barrier and higher surface-area-to-weight; per scoring rules exposure is increased by +1 (adult e=1 → baby e=2). No infant-specific mechanistic evidence was found. Sources: https://www.cir-safety.org/sites/default/files/TR_PaeoniaSuffruticosa_122024.pdf, https://echa.europa.eu/substance-information/-/substanceinfo/100.008.194, https://pubmed.ncbi.nlm.nih.gov/32058234/
- VeriMom은 paeonol을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 paeonol을 93/100 (알려진 위험 없음)로 평가합니다.
- 임신 중 paeonol 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.