octoxynol-9은 임신 중 안전한가요?
CIR’s final/amended safety assessment concluded octoxynols (including octoxynol‑9) are safe as used in cosmetics and identified no harmonised reproductive hazard; a dedicated rat teratology study with intravaginal octoxynol‑9 reported no maternal or fetal developmental effects. However, in vitro and in vivo data show that octylphenol (the de‑ethoxylation product) is estrogenic — a mechanistic concern for the parent phenol exists but not demonstrated for octoxynol‑9 in pregnancy at cosmetic exposures. Skin absorption data in the safety assessment indicate low but measurable absorption from topical formulations, so exposure (e) is scored as 1 (low but measurable). Sources: CIR safety assessment; rat teratology study; review on 4‑tert‑octylphenol.
Pregnancy-safe products containing octoxynol-9
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Frequently asked questions
- octoxynol-9은 임신 중 안전한가요?
- CIR’s final/amended safety assessment concluded octoxynols (including octoxynol‑9) are safe as used in cosmetics and identified no harmonised reproductive hazard; a dedicated rat teratology study with intravaginal octoxynol‑9 reported no maternal or fetal developmental effects. However, in vitro and in vivo data show that octylphenol (the de‑ethoxylation product) is estrogenic — a mechanistic concern for the parent phenol exists but not demonstrated for octoxynol‑9 in pregnancy at cosmetic exposures. Skin absorption data in the safety assessment indicate low but measurable absorption from topical formulations, so exposure (e) is scored as 1 (low but measurable). Sources: CIR safety assessment; rat teratology study; review on 4‑tert‑octylphenol.
- octoxynol-9은 모유 수유 중 안전한가요?
- No authoritative safety assessment (CIR) or harmonised classification flags reproductive/teratogenic effects for octoxynol‑9 and clinical/breastfeeding specific adverse outcomes are not reported in the high‑priority literature. Lactation databases and older clinical reports on related spermicides (nonoxynol‑9) did not show infant harm; nevertheless, low systemic absorption is possible and theoretical transfer in milk cannot be entirely excluded, so exposure is scored as 1 (low but measurable).
- octoxynol-9은 아기 피부에 안전한가요?
- CIR concluded octoxynols are safe as used but noted irritation concerns for some uses; skin absorption studies cited in the CIR/amended report indicate measurable absorption for octoxynols. Because infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier, exposure is increased by +1 relative to adults (adult e=1 → baby e=2). There is no infant‑specific evidence demonstrating elevated hazard or a different mechanism in babies.
- VeriMom은 octoxynol-9을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 octoxynol-9을 93/100 (알려진 위험 없음)로 평가합니다.
- 임신 중 octoxynol-9 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.




