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octocrylene은 임신 중 안전한가요?

No EU ban or harmonised CLP CMR classification exists; regulatory dossiers and a recent comprehensive toxicology review report no reproductive/developmental effects in the extended one‑generation rat study (NOAEL ~153 mg/kg/day), but in vitro and some non‑mammalian studies show endocrine‑related activity (e.g., PPARγ partial agonism) — supporting a precautionary hazard flag (h=1) with a demonstrated mechanistic signal (m=2). Sources: ECHA registration dossier; comprehensive review (Crit Rev Toxicol. 2025); peer‑reviewed PPARγ study; EWG noting dermal absorption.

성분
octocrylene
중간 위험
60
/100
0

임신 중 octocrylene 대체 안전 성분 | VeriMom

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Frequently asked questions

octocrylene은 임신 중 안전한가요?
No EU ban or harmonised CLP CMR classification exists; regulatory dossiers and a recent comprehensive toxicology review report no reproductive/developmental effects in the extended one‑generation rat study (NOAEL ~153 mg/kg/day), but in vitro and some non‑mammalian studies show endocrine‑related activity (e.g., PPARγ partial agonism) — supporting a precautionary hazard flag (h=1) with a demonstrated mechanistic signal (m=2). Sources: ECHA registration dossier; comprehensive review (Crit Rev Toxicol. 2025); peer‑reviewed PPARγ study; EWG noting dermal absorption.
octocrylene은 모유 수유 중 안전한가요?
Same evidence base as for pregnancy: no harmonised reproductive hazard or EU ban, animal reproduction data show high NOAELs and no clear reproductive/developmental adverse effects, but demonstrated in vitro endocrine activity and measurable dermal absorption mean a low precautionary concern for lactation (h=1, m=2) and low but measurable exposure to breast tissue/milk is plausible from topical use (e=1). Sources: ECHA registration dossier; Crit Rev Toxicol. 2025; PubMed studies; EWG.
octocrylene은 아기 피부에 안전한가요?
Hazard and mechanistic scores mirror adults (h=1, m=2) because no infant‑specific reproductive mechanism evidence was found; exposure score increased by +1 for infants due to higher skin permeability and surface‑area‑to‑weight (e=2). Dermal absorption of octocrylene is documented and infant skin is more permeable, so exposure is higher though direct infant toxicokinetic data are limited. Sources: EWG Skin Deep; Crit Rev Toxicol. 2025; ECHA registration materials.
VeriMom은 octocrylene을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 octocrylene을 60/100 (중간 위험)로 평가합니다.
임신 중 octocrylene 대체 안전 성분은?
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