n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine은 임신 중 안전한가요?

임신 중 n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine 대체 안전 성분 | VeriMom

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n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine은 임신 중 안전한가요?

SCCS concluded the substance is not safe for use as a hair‑dye because genotoxicity could not be ruled out; the ingredient is a secondary amine prone to nitrosation (theoretical formation of nitrosamines, which are reproductive/developmental toxicants in some cases), so I assign a structural/class‑based reproductive concern (h=1) and a theoretical mechanism via nitrosation (m=1). Topical use in hair dyes at up to ~1% on‑head gives low but measurable exposure (e=1). Source: SCCS opinion and submissions; note secondary‑amine / nitrosation statement.

n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine은 모유 수유 중 안전한가요?

Same rationale as for pregnancy: no direct reproductive/ lactation studies were found, but SCCS safety concerns (uncertainty about genotoxicity) and the compound’s propensity to nitrosate support a structural/theoretical concern (h=1, m=1). Dermal use leads to low but measurable exposure — breastfeeding exposure via maternal systemic absorption is therefore low but possible (e=1).

n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine은 아기 피부에 안전한가요?

No infant‑specific toxicology was located. Per instructions, because adult topical exposure is measurable (e=1) and infant skin has higher uptake, increase exposure score by +1 to e=2. Hazard and mechanism remain theoretical (h=1, m=1) in absence of direct developmental/infant data. SCCS restricted use for hair application; secondary‑amine nitrosation remains a contamination/indirect concern for infants.

VeriMom은 n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine을 어떻게 평가하나요?

VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine을 67/100 (중간 위험)로 평가합니다.

임신 중 n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine 대체 안전 성분은?

유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.