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melia azadirachta (neem) extract은 임신 중 안전한가요?

Animal studies reported reproductive effects after systemic (oral) dosing of neem/Melia extracts (e.g., inhibition of folliculogenesis in rats; maternal‑fetal study showed a change in sternal ossification at high oral dose), and this constitutes animal reproductive evidence warranting a 'suspected' reproductive hazard. There is no EU Annex II/III listing or harmonised CLP classification for the CAS 90063-92-6 extract, and no SCCS or CIR cosmetic opinion that overrides the animal data. (See PubMed studies and safety/review sources below).

성분
melia azadirachta (neem) extract
중간 위험
47
/100
0

임신 중 melia azadirachta (neem) extract 대체 안전 성분 | VeriMom

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melia azadirachta (neem) extract은 임신 중 안전한가요?
Animal studies reported reproductive effects after systemic (oral) dosing of neem/Melia extracts (e.g., inhibition of folliculogenesis in rats; maternal‑fetal study showed a change in sternal ossification at high oral dose), and this constitutes animal reproductive evidence warranting a 'suspected' reproductive hazard. There is no EU Annex II/III listing or harmonised CLP classification for the CAS 90063-92-6 extract, and no SCCS or CIR cosmetic opinion that overrides the animal data. (See PubMed studies and safety/review sources below).
melia azadirachta (neem) extract은 모유 수유 중 안전한가요?
Same rationale as pregnancy: systemic animal reproductive/developmental findings after oral dosing indicate a suspected hazard if there were systemic exposure. For topical cosmetic use breastfeeding exposure is expected to be negligible, but systemic maternal exposure (oral or high systemic) could be relevant. No authoritative regulatory breastfeeding-specific restrictions found.
melia azadirachta (neem) extract은 아기 피부에 안전한가요?
Hazard (h) remains at 2 because the scoring is driven by animal reproductive/developmental evidence. Mechanistic evidence (enzyme/biological activity of neem constituents and reported effects on follicles/ossification in animal studies) supports m=2. For exposure (e) increase by +1 for infants (immature skin barrier and higher SA:BW) so e=1 for baby (0–3 yr) topical scenarios; adult topical absorption for cosmetic use is judged low/negligible.
VeriMom은 melia azadirachta (neem) extract을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 melia azadirachta (neem) extract을 47/100 (중간 위험)로 평가합니다.
임신 중 melia azadirachta (neem) extract 대체 안전 성분은?
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