VeriMomdisodium glycyrrhizate은 임신 중 안전한가요?
No EU Annex II/III restriction or harmonised CLP classification for disodium glycyrrhizate was found, and CIR’s Final Report assessed disodium glycyrrhizate among licorice‑derived ingredients used in cosmetics and concluded safety in cosmetic use conditions. However, glycyrrhizic acid (parent molecule) has a demonstrated mechanism — inhibition of 11β‑HSD2 — producing mineralocorticoid effects and has been associated with adverse fetal/neonatal outcomes after maternal ingestion in epidemiological and animal studies; because this is a demonstrated endocrine mechanism it raises a suspected reproductive hazard for pregnancy when systemic exposure is possible. Sources: CIR final report (safety assessment covering disodium glycyrrhizate). Evidence of reproductive/foetal effects after oral licorice/glycyrrhizin exposure (epidemiology and animal studies). CosIng/EU ingredient listing supports cosmetic use but not a ban or restriction.
임신 중 disodium glycyrrhizate 대체 안전 성분 | VeriMom
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- disodium glycyrrhizate은 임신 중 안전한가요?
- No EU Annex II/III restriction or harmonised CLP classification for disodium glycyrrhizate was found, and CIR’s Final Report assessed disodium glycyrrhizate among licorice‑derived ingredients used in cosmetics and concluded safety in cosmetic use conditions. However, glycyrrhizic acid (parent molecule) has a demonstrated mechanism — inhibition of 11β‑HSD2 — producing mineralocorticoid effects and has been associated with adverse fetal/neonatal outcomes after maternal ingestion in epidemiological and animal studies; because this is a demonstrated endocrine mechanism it raises a suspected reproductive hazard for pregnancy when systemic exposure is possible. Sources: CIR final report (safety assessment covering disodium glycyrrhizate). Evidence of reproductive/foetal effects after oral licorice/glycyrrhizin exposure (epidemiology and animal studies). CosIng/EU ingredient listing supports cosmetic use but not a ban or restriction.
- disodium glycyrrhizate은 모유 수유 중 안전한가요?
- Mechanistic evidence (11β‑HSD2 inhibition by glycyrrhizic acid) is demonstrated and oral maternal intake of glycyrrhizin can lead to systemic effects; this supports a suspected hazard for breastfeeding if maternal systemic exposure is significant. Topical cosmetic use is expected to give low systemic absorption, so breastfeeding exposure from cosmetic topical use is likely low (measurable but small). CIR assessed cosmetic salts (including disodium glycyrrhizate) as safe as used; no harmonised CLP or EU ban/restriction was found.
- disodium glycyrrhizate은 아기 피부에 안전한가요?
- No harmonised classification or EU ban/restriction for disodium glycyrrhizate; CIR concluded cosmetic use is acceptable. The parent molecule has a demonstrated mechanism (11β‑HSD2 inhibition), so a mechanistic flag exists. For topical use on infant skin, absorption is higher (immature barrier and higher surface‑area‑to‑weight) so exposure score is increased; however there is no direct infant dermal reproductive/toxicology data showing harm from cosmetic topical use. Therefore hazard is scored as 1 (class/mechanistic concern present but no direct dermal reproductive evidence for the cosmetic salt).
- VeriMom은 disodium glycyrrhizate을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 disodium glycyrrhizate을 40/100 (중간 위험)로 평가합니다.
- 임신 중 disodium glycyrrhizate 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.