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cucurbitacin b은 임신 중 안전한가요?

No EU Annex II/III listing or harmonised CLP (no H360/H361 found). Peer‑reviewed studies show biologic activity and developmental effects in invertebrates (Drosophila) and multiple cytotoxic/anti‑proliferative effects in mammalian cell and cancer models, but I found no mammalian reproductive/developmental teratology studies showing fetal malformation in rodents or a harmonised reproductive classification — so classify as a structural/class concern (triterpenoid cytotoxin) rather than confirmed reproductive toxicant. Key sources: PubMed Drosophila developmental study and reviews showing potent bioactivity/cytotoxicity.

성분
cucurbitacin b
중간 위험
67
/100
0

임신 중 cucurbitacin b 대체 안전 성분 | VeriMom

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cucurbitacin b은 임신 중 안전한가요?
No EU Annex II/III listing or harmonised CLP (no H360/H361 found). Peer‑reviewed studies show biologic activity and developmental effects in invertebrates (Drosophila) and multiple cytotoxic/anti‑proliferative effects in mammalian cell and cancer models, but I found no mammalian reproductive/developmental teratology studies showing fetal malformation in rodents or a harmonised reproductive classification — so classify as a structural/class concern (triterpenoid cytotoxin) rather than confirmed reproductive toxicant. Key sources: PubMed Drosophila developmental study and reviews showing potent bioactivity/cytotoxicity.
cucurbitacin b은 모유 수유 중 안전한가요?
Same basis as pregnancy: biological activity and cytotoxicity in vitro and in vivo cancer models raise a plausible concern for systemic effects if absorbed, but there is no direct evidence of transfer into human milk or documented nursing-infant adverse outcomes. No harmonised CMR classification found to elevate hazard to h≥2.
cucurbitacin b은 아기 피부에 안전한가요?
No infant‑specific toxicity data. Because cucurbitacin B is a biologically active, low‑molecular‑weight triterpenoid with demonstrated cellular toxicity, assign a class/structural concern (h=1). Dermal absorption data are lacking; immature infant skin increases exposure potential so exposure score is increased (+1) to e=2 for 0–3 yr old skin. No infant dermal irritation/systemic developmental studies were found.
VeriMom은 cucurbitacin b을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 cucurbitacin b을 67/100 (중간 위험)로 평가합니다.
임신 중 cucurbitacin b 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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