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capryloyl salicylic acid은 임신 중 안전한가요?

Animal developmental data show effects at high doses (dermal application in pregnant rats: increased incomplete ossification at 100 mg/kg/day; NOAEL for developmental toxicity 40 mg/kg/day), so reproductive/developmental hazard is suspected based on animal evidence; there is no harmonised CLP reproductive classification and CIR concluded cosmetic use at reported concentrations is safe. Dermal absorption in vitro is low but measurable (~6% penetrated deeper than the stratum corneum in a 16 h Franz cell study), so exposure from typical topical cosmetic use is low but measurable.

성분
capryloyl salicylic acid
중간 위험
53
/100
0

Pregnancy-safe products containing capryloyl salicylic acid

임신 중 capryloyl salicylic acid 대체 안전 성분 | VeriMom

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Frequently asked questions

capryloyl salicylic acid은 임신 중 안전한가요?
Animal developmental data show effects at high doses (dermal application in pregnant rats: increased incomplete ossification at 100 mg/kg/day; NOAEL for developmental toxicity 40 mg/kg/day), so reproductive/developmental hazard is suspected based on animal evidence; there is no harmonised CLP reproductive classification and CIR concluded cosmetic use at reported concentrations is safe. Dermal absorption in vitro is low but measurable (~6% penetrated deeper than the stratum corneum in a 16 h Franz cell study), so exposure from typical topical cosmetic use is low but measurable.
capryloyl salicylic acid은 모유 수유 중 안전한가요?
No direct data on excretion in milk were identified; because animal developmental effects exist (see pregnancy section) the ingredient is treated as a suspected reproductive/developmental hazard. Maternal topical exposure gives low but measurable dermal penetration (CIR data), so systemic exposure cannot be excluded though milk transfer data are absent.
capryloyl salicylic acid은 아기 피부에 안전한가요?
Do not increase hazard without infant-specific evidence; however exposure score is increased by +1 for infants because CIR reports measurable dermal penetration in adults (~6% beyond stratum corneum and ~17% in stratum corneum by tape‑strip), and infant skin has higher absorption per weight. There are no infant-specific safety studies; CIR considered cosmetic uses (max reported leave‑on 0.5%) acceptable given available data.
VeriMom은 capryloyl salicylic acid을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 capryloyl salicylic acid을 53/100 (중간 위험)로 평가합니다.
임신 중 capryloyl salicylic acid 대체 안전 성분은?
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