borago officinalis leaf extract은 임신 중 안전한가요?

임신 중 borago officinalis leaf extract 대체 안전 성분 | VeriMom

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borago officinalis leaf extract은 임신 중 안전한가요?

No EU Cosmetic Regulation ban (Annex II) or Annex III restriction or harmonised CLP H360/H361 was identified for Borago officinalis leaf extract. However, the plant family (Boraginaceae) is known to produce pyrrolizidine alkaloids (PAs) which have demonstrated toxic and genotoxic mechanisms in animals and humans; this represents a class-based concern (h=1) with a demonstrated mechanism (m=2). Topical cosmetic use of a leaf extract is likely low but measurable exposure (e=1). Sources: EU INCI listing for Borago Officinalis Extract, PubMed reviews on borage/PAs, and EWG ingredient summary.

borago officinalis leaf extract은 모유 수유 중 안전한가요?

Same rationale as pregnancy: no regulatory ban or harmonised reproductive classification found, but PA-related hepatotoxic/genotoxic concerns for Borago officinalis warrant a class-level caution (h=1). Mechanistic evidence for PA toxicity exists (m=2). Topical use implies low but measurable exposure (e=1); systemic transfer into breastmilk after dermal cosmetic use has not been demonstrated.

borago officinalis leaf extract은 아기 피부에 안전한가요?

Hazard (h=1) remains driven by the plant’s PA class concern rather than any infant-specific reproductive data. Mechanistic concern from PAs (m=2) remains. Exposure is increased for babies (elevated by +1 to e=2) because infant skin has higher surface-area-to-weight and an immature barrier, so topical absorption (if any) is proportionally higher even though absolute systemic exposure from a cosmetic extract is expected to be low.

VeriMom은 borago officinalis leaf extract을 어떻게 평가하나요?

VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 borago officinalis leaf extract을 60/100 (중간 위험)로 평가합니다.

임신 중 borago officinalis leaf extract 대체 안전 성분은?

유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.