VeriMomapigenin은 임신 중 안전한가요?
No EU Annex II/III listing or harmonised CLP reproductive/CMR classification was found for apigenin (CAS 520-36-5), and no authoritative CIR/SCCS safety opinion identifying a reproductive hazard was found; peer‑reviewed literature reports in‑vitro estrogenic/sex‑hormone–modulating activity for apigenin (mechanistic evidence) but not clear human teratogenic or harmonised animal reproductive hazard leading to regulatory classification, so hazard = 0; mechanism = 2 because in‑vitro estrogenic and endocrine‑modulating activity has been demonstrated. Topical dermal absorption from cosmetics is reported as low but measurable depending on formulation (ex vivo permeation varies with vehicle), therefore exposure = 1. � Sources: PubMed/PMC reviews on apigenin bioactivity and skin use; ex vivo skin permeation review; COSING/ingredient databases.
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Frequently asked questions
- apigenin은 임신 중 안전한가요?
- No EU Annex II/III listing or harmonised CLP reproductive/CMR classification was found for apigenin (CAS 520-36-5), and no authoritative CIR/SCCS safety opinion identifying a reproductive hazard was found; peer‑reviewed literature reports in‑vitro estrogenic/sex‑hormone–modulating activity for apigenin (mechanistic evidence) but not clear human teratogenic or harmonised animal reproductive hazard leading to regulatory classification, so hazard = 0; mechanism = 2 because in‑vitro estrogenic and endocrine‑modulating activity has been demonstrated. Topical dermal absorption from cosmetics is reported as low but measurable depending on formulation (ex vivo permeation varies with vehicle), therefore exposure = 1. � Sources: PubMed/PMC reviews on apigenin bioactivity and skin use; ex vivo skin permeation review; COSING/ingredient databases.
- apigenin은 모유 수유 중 안전한가요?
- Same rationale as pregnancy: no regulatory reproductive/CMR classification or CIR/SCCS restriction found. Mechanistic data show apigenin can modulate hormone pathways (in vitro) which is relevant to lactation physiology but no convincing data show human reproductive or lactation toxicity. Dermal exposure from cosmetics is low but measurable, so adult breastfeeding exposure = 1. Sources: peer‑reviewed reviews on apigenin pharmacology and topical use; COSING/EWG entries.
- apigenin은 아기 피부에 안전한가요?
- No infant‑specific developmental toxicity or dermal teratogenicity data were found and no regulatory ban/restriction for apigenin. Mechanistic evidence (in‑vitro estrogenic/endocrine‑modulating activity) remains (m=2). Exposure score increased by +1 for infants (e=2) because topical absorption through infant skin is higher (immature barrier, higher surface‑area‑to‑weight) and formulation/permeation studies show apigenin can permeate skin depending on vehicle; therefore infant dermal exposure is likely higher than adult. Sources: reviews showing skin permeation and cosmetic use, PubMed mechanistic literature, COSING database.
- VeriMom은 apigenin을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 apigenin을 80/100 (낮은 위험)로 평가합니다.
- 임신 중 apigenin 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.