임신 중 trimethyl pentanyl diisobutyrate을 피해야 할까요? | VeriMom

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Pregnancy-safe ingredients that serve a similar function:

FAQ

trimethyl pentanyl diisobutyrate은 임신 중 안전한가요?

Trimethyl pentanyl diisobutyrate (TXIB; CAS 6846-50-0) has a harmonised/suspected reproductive hazard classification (H361) in regulatory sources and registration dossiers reporting reduced implant numbers and reduced litter weights in an OECD 421 rat study, supporting a suspected reproductive hazard. (ECHA registration dossier and SDS reporting H361; see sources). In vitro and ex vivo studies (fetal testis organ culture; gonadal cell lines) show biologically plausible effects on reproductive endpoints/sex-hormone related parameters, indicating a demonstrated mechanistic signal. Topical cosmetic exposure would generally give low but measurable systemic exposure (so e=1) for pregnant adults absent product-specific dermal absorption data.

trimethyl pentanyl diisobutyrate은 모유 수유 중 안전한가요?

Same hazard basis applies (harmonised H361 / OECD 421 reproductive findings). Mechanistic data (in vitro/ex vivo endocrine-related effects and interactions with sex-hormone binding protein) support potential for reproductive/endocrine activity. With typical topical cosmetic use, maternal systemic exposure is expected to be low but measurable; specific data on transfer into human milk are not available, so exposure is scored as low (e=1).

trimethyl pentanyl diisobutyrate은 아기 피부에 안전한가요?

Hazard and mechanistic evidence remain the same (H361; animal reproductive/developmental signals; in vitro/ex vivo endocrine-related findings). Infant skin has higher absorption per kg, so exposure score is increased by +1 versus adults (adult e=1 → baby e=2) in the absence of definitive dermal absorption data for cosmetic formulations intended for infants.

VeriMom은 trimethyl pentanyl diisobutyrate을 어떻게 평가하나요?

VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 trimethyl pentanyl diisobutyrate을 20/100 (높은 위험)로 평가합니다.

임신 중 trimethyl pentanyl diisobutyrate 대체 안전 성분은?

유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.