임신 중 theophylline을 피해야 할까요? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

theophylline은 임신 중 안전한가요?

Animal studies (mouse continuous-breeding, NTP/NIEHS; and rabbit developmental studies) report reduced pup numbers, fetal effects and teratogenicity at high systemic doses, supporting a suspected reproductive/developmental hazard. Theophylline crosses the placenta in humans/animals (demonstrated placental transfer). For topical cosmetic use maternal systemic exposure is likely low but measurable, so exposure to the fetus from maternal use is possible but expected to be limited. (Sources: NTP reproductive study; rabbit teratogenicity study; pharmacokinetic/label notes on placental transfer).

theophylline은 모유 수유 중 안전한가요?

Theophylline is known to be excreted into human breast milk and neonatal effects have been reported following maternal administration; animal reproductive/developmental evidence also exists. Mechanistic evidence includes demonstrated transfer into milk. For topical cosmetic use maternal systemic uptake is likely low but measurable so infant exposure via milk is possible but expected to be limited for cosmetic use.

theophylline은 아기 피부에 안전한가요?

Animal data indicate reproductive/developmental toxicity at systemic doses; theophylline also crosses biological barriers (placenta, milk) indicating demonstrated distribution. Infant skin (0–3 yr) has higher dermal uptake per surface-area-to-weight; therefore exposure (e) is increased by +1 versus adults when the ingredient has measurable absorption. There is no infant-specific data showing a different hazard classification, but systemic developmental/neurologic concerns from theophylline support a suspected hazard for infants if systemic exposure occurs.

VeriMom은 theophylline을 어떻게 평가하나요?

VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 theophylline을 20/100 (높은 위험)로 평가합니다.

임신 중 theophylline 대체 안전 성분은?

유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.