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임신 중 silybum marianum extract을 피해야 할까요? | VeriMom

No harmonised CLP classification (no H360/H361 harmonised entry found), no EU Annex II/III restriction for Silybum marianum extract. Recent reviews and animal studies show either absence of reproductive/developmental toxicity or protective effects from silymarin; human data in pregnancy are scarce so regulators (NCCIH/EMA summaries) caution use but do not list a reproductive hazard. Topical cosmetic use would give low but measurable exposure. Sources: PubMed reviews and animal studies, NCCIH, ECHA registration summary. (PubMed review: Protective effects of silymarin on reproductive toxicity; animal developmental study: silymarin during pregnancy/lactation; NCCIH: limited data on pregnancy/breastfeeding; ECHA registration/listing shows registration dossier but no harmonised H361 classification).

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

silybum marianum extract은 임신 중 안전한가요?
No harmonised CLP classification (no H360/H361 harmonised entry found), no EU Annex II/III restriction for Silybum marianum extract. Recent reviews and animal studies show either absence of reproductive/developmental toxicity or protective effects from silymarin; human data in pregnancy are scarce so regulators (NCCIH/EMA summaries) caution use but do not list a reproductive hazard. Topical cosmetic use would give low but measurable exposure. Sources: PubMed reviews and animal studies, NCCIH, ECHA registration summary. (PubMed review: Protective effects of silymarin on reproductive toxicity; animal developmental study: silymarin during pregnancy/lactation; NCCIH: limited data on pregnancy/breastfeeding; ECHA registration/listing shows registration dossier but no harmonised H361 classification).
silybum marianum extract은 모유 수유 중 안전한가요?
Human data are limited. Some small/unpublished reports suggest low or non‑measurable excretion of silymarin into breastmilk, but evidence is insufficient and agencies advise caution. Topical cosmetic exposure would result in low systemic levels for the lactating parent, so infant exposure via milk from topical use is expected to be low but not zero. (Sources: NCCIH, EFSA/EFSA‑referenced report, PubMed studies).
silybum marianum extract은 아기 피부에 안전한가요?
No direct evidence of developmental or infant dermal toxicity. Because infants 0–3 years have a thinner/immature skin barrier and higher surface‑area‑to‑body‑weight, exposure score is increased by +1 compared with adults if the ingredient has measurable absorption. Silymarin components are moderately lipophilic and can be absorbed to a small degree; therefore infant dermal exposure is assessed as moderate. No infant‑specific hazards or CMR classifications were identified. (Sources: PubMed reviews, ECHA registration dossier, EWG ingredient page).
VeriMom은 silybum marianum extract을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 silybum marianum extract을 33/100 (높은 위험)로 평가합니다.
임신 중 silybum marianum extract 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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