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임신 중 sassafras officinale bark extract을 피해야 할까요? | VeriMom

Sassafras bark/root extracts can contain the alkenylbenzene safrole, which is harmonised/classified in the EU as a carcinogen (CLP Category 1B/H350/H351) and is prohibited in cosmetics; carcinogenic/mutagenic hazards are treated as high reproductive concern. Safrole’s metabolic activation leads to DNA adduct formation (demonstrated mechanism). Exposure from topical cosmetic use is low–but measurable unless the extract is guaranteed safrole-free. (ECHA substance data; NTP/Report on Carcinogens; PubMed reviews of alkenylbenzenes).

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FAQ

sassafras officinale bark extract은 임신 중 안전한가요?
Sassafras bark/root extracts can contain the alkenylbenzene safrole, which is harmonised/classified in the EU as a carcinogen (CLP Category 1B/H350/H351) and is prohibited in cosmetics; carcinogenic/mutagenic hazards are treated as high reproductive concern. Safrole’s metabolic activation leads to DNA adduct formation (demonstrated mechanism). Exposure from topical cosmetic use is low–but measurable unless the extract is guaranteed safrole-free. (ECHA substance data; NTP/Report on Carcinogens; PubMed reviews of alkenylbenzenes).
sassafras officinale bark extract은 모유 수유 중 안전한가요?
Same basis as pregnancy: presence of safrole (harmonised EU classification as a CMR) makes the ingredient high hazard for lactation context. Topical exposures are low–but measurable; transfer into milk is not well characterised for cosmetic topical use, but CMR classification and genotoxic mechanism justify a high hazard rating. (ECHA; NTP; SCF/PubMed reviews).
sassafras officinale bark extract은 아기 피부에 안전한가요?
Hazard and mechanism mirror adult/pregnancy because safrole is a harmonised CMR 1B. Exposure score is increased for infants (+1) because infant skin has higher surface-area-to-weight and less mature barrier, so a measurable topical exposure becomes a moderate exposure for 0–3 yr. Where the extract is confirmed safrole-free, these scores would change. (ECHA; NTP; PubMed reviews).
VeriMom은 sassafras officinale bark extract을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 sassafras officinale bark extract을 20/100 (높은 위험)로 평가합니다.
임신 중 sassafras officinale bark extract 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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