임신 중 quaternium-15을 피해야 할까요? | VeriMom
Quaternium‑15 (CAS 4080‑31‑3 / mixed cis/trans and cis isomer CAS variants) has been regulated as a CMR (toxic for reproduction) concern in the EU and has been moved into Annex II (prohibited in cosmetics) following classification of the cis‑isomer as a reproductive toxicant; harmonised/authoritative sources and regulatory reviews report reproductive/teratogenic findings in animals. Because of that regulatory action (EU Annex II / Commission Regulation amending 1223/2009) and reported animal findings, the hazard score is 2. Mechanistically, quaternium‑15 is a formaldehyde‑releasing preservative and there are animal reproduction/developmental toxicity findings reported in regulatory reviews, so mechanism is scored as demonstrated (2). Topical cosmetic exposures give low but measurable systemic exposure for most formaldehyde releasers, therefore exposure is scored 1 for pregnancy. (Sources: EU Commission Regulation / Annex II amendment; SCCS/CIR/regulatory reviews; animal studies.)
ECHA regulatory hazard statements
- •H361
- •H361D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- quaternium-15은 임신 중 안전한가요?
- Quaternium‑15 (CAS 4080‑31‑3 / mixed cis/trans and cis isomer CAS variants) has been regulated as a CMR (toxic for reproduction) concern in the EU and has been moved into Annex II (prohibited in cosmetics) following classification of the cis‑isomer as a reproductive toxicant; harmonised/authoritative sources and regulatory reviews report reproductive/teratogenic findings in animals. Because of that regulatory action (EU Annex II / Commission Regulation amending 1223/2009) and reported animal findings, the hazard score is 2. Mechanistically, quaternium‑15 is a formaldehyde‑releasing preservative and there are animal reproduction/developmental toxicity findings reported in regulatory reviews, so mechanism is scored as demonstrated (2). Topical cosmetic exposures give low but measurable systemic exposure for most formaldehyde releasers, therefore exposure is scored 1 for pregnancy. (Sources: EU Commission Regulation / Annex II amendment; SCCS/CIR/regulatory reviews; animal studies.)
- quaternium-15은 모유 수유 중 안전한가요?
- Same hazard/mechanism as for pregnancy (regulatory classification and animal data). With typical topical cosmetic use, systemic absorption is expected to be low; therefore breastmilk exposure potential is low but not zero — exposure scored 1. No specific breast‑milk transfer studies located in the reviewed sources.
- quaternium-15은 아기 피부에 안전한가요?
- Hazard and mechanism remain driven by the same regulatory and animal evidence (EU prohibition based on CMR classification of the cis‑isomer and reported developmental toxicity). Exposure score is increased by +1 for infants (per instruction) because infant skin barrier immaturity and higher surface‑area‑to‑weight ratio make low but measurable percutaneous absorption more relevant; therefore baby exposure scored 2. Note: quaternium‑15 is also a known skin sensitizer in humans, increasing concern for infant dermal irritation/allergy.
- VeriMom은 quaternium-15을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 quaternium-15을 20/100 (높은 위험)로 평가합니다.
- 임신 중 quaternium-15 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.