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임신 중 psoralea corylifolia fruit extract을 피해야 할까요? | VeriMom

Animal and in vitro studies report embryotoxicity and reproductive/developmental effects for Psoralea corylifolia extracts and its constituents (psoralens, bakuchiol), supporting a suspected reproductive hazard (h=2). Reviews and primary studies describe embryotoxicity and developmental toxicity in animal models and identify estrogenic activity for bakuchiol (mechanism demonstrated → m=2). Topical exposure is plausibly systemically available for psoralens and other small lipophilic constituents (percutaneous absorption and phototoxicity documented) so exposure from cosmetics is moderate (e=2). Sources: PMC review (systematic toxicology summary) and primary embryotoxicity/reproductive studies. (See sources list.)

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FAQ

psoralea corylifolia fruit extract은 임신 중 안전한가요?
Animal and in vitro studies report embryotoxicity and reproductive/developmental effects for Psoralea corylifolia extracts and its constituents (psoralens, bakuchiol), supporting a suspected reproductive hazard (h=2). Reviews and primary studies describe embryotoxicity and developmental toxicity in animal models and identify estrogenic activity for bakuchiol (mechanism demonstrated → m=2). Topical exposure is plausibly systemically available for psoralens and other small lipophilic constituents (percutaneous absorption and phototoxicity documented) so exposure from cosmetics is moderate (e=2). Sources: PMC review (systematic toxicology summary) and primary embryotoxicity/reproductive studies. (See sources list.)
psoralea corylifolia fruit extract은 모유 수유 중 안전한가요?
Because systemic maternal exposure is plausible and animal data indicate reproductive/developmental toxicity, the ingredient is rated as suspected (h=2) for breastfeeding. Mechanistic data (psoralens, bakuchiol with demonstrated bioactivity including estrogenic effects) support m=2. Dermal/topical use can result in systemic absorption of psoralens/bakuchiol (documented in percutaneous studies), so exposure to nursing parent is moderate (e=2); no reliable data on milk transfer were identified.
psoralea corylifolia fruit extract은 아기 피부에 안전한가요?
Infant-specific evidence was not found, so hazard and mechanism scores match adult (h=2, m=2). Exposure score increased by +1 for baby skin (immature barrier and higher surface-area-to-weight) from adult e=2 to e=3; psoralens and other small constituents in extracts have measurable dermal absorption/phototoxicity, raising exposure concern for 0–3 yr skin.
VeriMom은 psoralea corylifolia fruit extract을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 psoralea corylifolia fruit extract을 33/100 (높은 위험)로 평가합니다.
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