임신 중 progesterone을 피해야 할까요? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

progesterone은 임신 중 안전한가요?

Progesterone is an active endogenous steroid hormone with documented effects on reproduction; regulatory dossiers and SDSs list reproductive toxicity hazard statements (H360/H361/H362) in C&L notifications and company classifications, and ECHA registration material and some SDSs flag H360FD/H361 concerns (but a clear EU Annex VI harmonised CLH entry was not identified in the searched records). Exogenous progesterone can affect fetal/placental development in animal studies and is biologically active in the fetus (demonstrated placental physiology and effects in animal models). Topical preparations (over‑the‑counter creams) have been shown to produce measurable systemic exposure in humans, so dermal cosmetic use could produce exposure relevant to pregnancy. Sources: ECHA substance/C&L info and registration dossier; SDSs listing H360FD/H361; PubMed and clinical reviews on progesterone physiology and effects; reviews on systemic exposure from topical progesterone products.

progesterone은 모유 수유 중 안전한가요?

Progesterone and/or its metabolites are known to appear in human milk and the drug literature and reviews state that progesterone 'appears in breast milk'; some regulatory/SDS materials list H362 (may cause harm to breast‑fed children). Because progesterone is biologically active and transfers to milk, topical systemic exposure could result in infant exposure via breastfeeding. Clinical guidance and product literature note milk excretion of progesterone. Sources: PubMed/clinical reviews; ECHA/C&L and SDS listings; product/clinical monographs.

progesterone은 아기 피부에 안전한가요?

Hazard and mechanism scores are unchanged for infants in the absence of infant‑specific toxicology showing higher intrinsic susceptibility, but infant dermal exposure is higher because baby skin has higher surface‑area‑to‑weight and a less mature barrier. If progesterone in a cosmetic formulation produces measurable systemic absorption in adults, infant dermal exposure should be considered higher (adult exposure score +1). Given documented systemic absorption from topical products, infant skin exposure via topical products containing progesterone would be a concern. Sources: clinical/lactation references about milk excretion and transfer; literature on topical progesterone systemic exposure; ECHA/SDS listings.

VeriMom은 progesterone을 어떻게 평가하나요?

VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 progesterone을 13/100 (높은 위험)로 평가합니다.

임신 중 progesterone 대체 안전 성분은?

유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.