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임신 중 potassium nitrate을 피해야 할까요? | VeriMom

There are animal and mechanistic data linking nitrate/nitrite exposure to adverse prenatal outcomes at high doses (methemoglobinemia, inflammation, DNA damage and possible endocrine-related effects), and multiple supplier safety data sheets list H361 (suspected of damaging fertility/unborn child) although that appears to reflect CLP notifications/self-classifications rather than an EU harmonised Annex VI entry; therefore reproductive hazard is scored as 'suspected' (h=2). Evidence for mechanism (methemoglobinemia/nitrite conversion and inflammatory/DNA effects) is documented in a recent scoping review and older JECFA/INCHEN summaries. Topical cosmetic use is unlikely to give meaningful systemic nitrate exposure (low dermal uptake of inorganic salts) so exposure from normal cosmetic application is scored low/negligible (e=0). (Sources: PubMed scoping review; JECFA/INCHEN nitrate summary; ECHA substance/registration pages; representative SDSs and EWG entry.)

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

potassium nitrate은 임신 중 안전한가요?
There are animal and mechanistic data linking nitrate/nitrite exposure to adverse prenatal outcomes at high doses (methemoglobinemia, inflammation, DNA damage and possible endocrine-related effects), and multiple supplier safety data sheets list H361 (suspected of damaging fertility/unborn child) although that appears to reflect CLP notifications/self-classifications rather than an EU harmonised Annex VI entry; therefore reproductive hazard is scored as 'suspected' (h=2). Evidence for mechanism (methemoglobinemia/nitrite conversion and inflammatory/DNA effects) is documented in a recent scoping review and older JECFA/INCHEN summaries. Topical cosmetic use is unlikely to give meaningful systemic nitrate exposure (low dermal uptake of inorganic salts) so exposure from normal cosmetic application is scored low/negligible (e=0). (Sources: PubMed scoping review; JECFA/INCHEN nitrate summary; ECHA substance/registration pages; representative SDSs and EWG entry.)
potassium nitrate은 모유 수유 중 안전한가요?
Potential reproductive/developmental concern is the same as for pregnancy (animal evidence and mechanistic pathways via nitrate→nitrite/methemoglobinemia), so hazard is 'suspected' (h=2) and mechanism retained (m=2). Dermal cosmetic use in the lactating parent is unlikely to produce significant systemic levels to transfer via breastmilk, so exposure from typical topical cosmetic use is scored negligible (e=0).
potassium nitrate은 아기 피부에 안전한가요?
No infant-specific toxicology demonstrating greater hazard was found, so hazard and mechanism remain as for adults (h=2, m=2). However, infant skin has higher surface-area-to-weight and an immature barrier, and while potassium nitrate is an inorganic, water‑soluble salt with low dermal penetration, the baby exposure score is increased by +1 relative to adults to reflect greater per‑kg exposure potential from topical application (e=1).
VeriMom은 potassium nitrate을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 potassium nitrate을 27/100 (높은 위험)로 평가합니다.
임신 중 potassium nitrate 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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