임신 중 plectranthus barbatus root extract을 피해야 할까요? | VeriMom

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FAQ

plectranthus barbatus root extract은 임신 중 안전한가요?

No EU cosmetic ban/restriction was found for Plectranthus/Coleus (INCI listed in the EU Official Journal), but the root extract contains forskolin. Forskolin has been shown to induce endocrine disturbances in human placental JEG‑3 cells (in vitro) and an older rat study reported anti‑implantation/delayed fetal effects — therefore reproductive hazard is “suspected” (h=2) with a demonstrated mechanism (m=2). An in vitro skin diffusion study showed forskolin can permeate human skin and permeation is enhanced when delivered in the crude P. barbatus root extract, so topical exposure is measurable/moderate (e=2). Sources: EU CosIng/Official Journal; in vitro placental study (PMCID: PMC9317975); in vitro skin diffusion J Nat Prod (Chen et al.).

plectranthus barbatus root extract은 모유 수유 중 안전한가요?

There are no reliable human milk/excretion studies for Plectranthus/forskolin; guidance resources warn against oral use in pregnancy/lactation due to limited safety data. Because systemic exposure to forskolin could theoretically affect nursing infants but direct evidence for adverse effects via breastmilk is lacking, assign a low/class‑based concern (h=1) with a theoretical mechanism (m=1). Topical cosmetic use has low but measurable systemic absorption potential (e=1). Sources: LactMed/NCBI Monograph; WebMD summary; PMC placental study (mechanistic relevance).

plectranthus barbatus root extract은 아기 피부에 안전한가요?

No infant‑specific adverse dermatologic or developmental data were found for topical Plectranthus barbatus root extract. Per instructions, baby hazard (h) and mechanism (m) were not increased in the absence of infant‑specific evidence. However, because the extract (and forskolin within it) shows measurable skin permeation in vitro and infant skin has higher surface‑area‑to‑weight and immature barrier, exposure is increased for babies (+1 vs adult), giving e=3. Sources: J Nat Prod skin diffusion study; no baby‑specific safety studies located.

VeriMom은 plectranthus barbatus root extract을 어떻게 평가하나요?

VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 plectranthus barbatus root extract을 33/100 (높은 위험)로 평가합니다.

임신 중 plectranthus barbatus root extract 대체 안전 성분은?

유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.