임신 중 oxyquinoline을 피해야 할까요? | VeriMom
Quinolin-8-ol (oxyquinoline, CAS 148-24-3) has an EU harmonised classification as a reproductive toxicant (Repr. 1B — H360D: “may damage the unborn child”), which by your scoring rules requires h=3. Mechanistic data linking a specific reproductive pathway are limited (mutagenicity was reported in some assays but no well‑characterised developmental mechanism), so m is scored 1 (theoretical/limited). For typical topical cosmetic use (used at ≤1% in formulations per CIR), dermal uptake is plausible but not high, so exposure (e) for pregnancy is scored 1 (low but measurable). (Sources: ECHA/EUR‑Lex harmonised classification; CIR safety assessment.).
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- oxyquinoline은 임신 중 안전한가요?
- Quinolin-8-ol (oxyquinoline, CAS 148-24-3) has an EU harmonised classification as a reproductive toxicant (Repr. 1B — H360D: “may damage the unborn child”), which by your scoring rules requires h=3. Mechanistic data linking a specific reproductive pathway are limited (mutagenicity was reported in some assays but no well‑characterised developmental mechanism), so m is scored 1 (theoretical/limited). For typical topical cosmetic use (used at ≤1% in formulations per CIR), dermal uptake is plausible but not high, so exposure (e) for pregnancy is scored 1 (low but measurable). (Sources: ECHA/EUR‑Lex harmonised classification; CIR safety assessment.).
- oxyquinoline은 모유 수유 중 안전한가요?
- Because the substance has a harmonised Repr.1B/H360D classification (systemic reproductive hazard), the hazard to nursing is scored h=3 under your rules. There is no clear, well‑established mechanism specific to lactational transfer (m=1). Dermal cosmetic use gives low but potentially measurable systemic exposure (e=1), so transfer into milk cannot be excluded at trace levels; no robust human milk data were found in the reviewed sources.
- oxyquinoline은 아기 피부에 안전한가요?
- Do not increase hazard or mechanism absent infant‑specific data, so h=3 and m=1 as above. Because infant skin has higher permeability and surface‑area‑to‑weight, exposure score is increased by +1 from adult (adult e=1 → infant e=2), meaning moderate concern for systemic uptake from topical application to infant skin. No infant‑specific toxicokinetic or outcome studies were identified.
- VeriMom은 oxyquinoline을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 oxyquinoline을 27/100 (높은 위험)로 평가합니다.
- 임신 중 oxyquinoline 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.