ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
Pregnancy-safe products to use instead
Products built around the safer ingredients above, scored "no known risks" or "low risk".

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Sources & references
Authoritative references used to score this ingredient.
임신 중 nifedipine 대체 안전 성분 | VeriMom
성분 — 성분
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FAQ
- nifedipine은 임신 중 안전한가요?
- Nifedipine is a systemic pharmaceutical (a dihydropyridine Ca2+ channel blocker) with evidence of fetal exposure: PBPK and clinical studies report substantial transplacental transfer (cord:maternal ratios ≈ ~1 in modelling and clinical measurements), and supplier safety data sheets list reproductive toxicity H361 (suspected of damaging fertility or the unborn child). Because ECHA-harmonised H360 classification was not identified but H361 is reported in SDS/registrations, hazard is scored as 'suspected' (h=2); mechanism is 'demonstrated' (m=2) because placental transfer and pharmacodynamic effects on uteroplacental blood flow are reported; topical cosmetic exposure is likely low but systemic if used as a drug, so for cosmetic topical use exposure is low (e=1). (Sources: PBPK and placental studies, systematic reviews and SDSs.).
- nifedipine은 모유 수유 중 안전한가요?
- Nifedipine is excreted into breastmilk in measurable but generally small amounts and is commonly considered compatible with breastfeeding in clinical guidance; supplier SDSs list reproductive toxicity H361 which supports a suspected reproductive hazard (h=2). Mechanistically, milk transfer is documented (so m=1–2), but adverse effects in infants are not robustly reported in the clinical literature; for topical cosmetic use exposure is expected to be low (e=1).
- nifedipine은 아기 피부에 안전한가요?
- There is no infant-specific dermal hazard data for 0–3 yr; nifedipine is systemically active and can cross placenta / enter milk, so parental systemic concern remains (h=2). For baby skin, because infants have higher skin absorption and the parent compound is moderately lipophilic (not completely non-absorbable), increase exposure score by +1 relative to adult topical use (adult e=1 → infant e=2). No direct evidence supports increasing hazard or mechanism beyond adult data in absence of infant-specific studies.
- VeriMom은 nifedipine을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 nifedipine을 20/100 (높은 위험)로 평가합니다.
- 임신 중 nifedipine 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.