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임신 중 methoxydiglycol을 피해야 할까요? | VeriMom

ECHA lists diethylene glycol monomethyl ether (methoxydiglycol, CAS 111-77-3) with a harmonised CLP classification for reproductive toxicity (H360 - may damage fertility or the unborn child), which places it in the highest hazard band for developmental/reproductive effects. Animal and mechanistic work show it is metabolised to methoxyacetic acid, a metabolite implicated in reproductive/developmental toxicity in multiple studies, supporting a demonstrated mechanism. Dermal/topical use gives measurable systemic absorption for small glycols used as solvents, so exposure from cosmetics is non‑negligible (moderate). ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))

ECHA regulatory hazard statements

  • H360D

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

methoxydiglycol은 임신 중 안전한가요?
ECHA lists diethylene glycol monomethyl ether (methoxydiglycol, CAS 111-77-3) with a harmonised CLP classification for reproductive toxicity (H360 - may damage fertility or the unborn child), which places it in the highest hazard band for developmental/reproductive effects. Animal and mechanistic work show it is metabolised to methoxyacetic acid, a metabolite implicated in reproductive/developmental toxicity in multiple studies, supporting a demonstrated mechanism. Dermal/topical use gives measurable systemic absorption for small glycols used as solvents, so exposure from cosmetics is non‑negligible (moderate). ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
methoxydiglycol은 모유 수유 중 안전한가요?
Because the substance has a harmonised H360 reproductive classification and is metabolised to methoxyacetic acid (a known reproductive toxicant), there is concern for transfer to nursing infants; advisory bodies note uncertainty but flag lactation as a relevant route and the absence of data on milk levels. Dermal/topical use can produce systemic levels (measurable), so breastfeeding exposure cannot be ruled out. ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
methoxydiglycol은 아기 피부에 안전한가요?
Hazard (H360) remains highest (h=3) due to harmonised CLP classification and animal evidence. Mechanistic concern (metabolism to methoxyacetic acid) is demonstrated. Exposure (e) is increased by +1 for infants (per your instruction): because the compound is a small, moderately skin‑permeable solvent with measurable dermal uptake in adults, infant skin (higher SA:weight and immature barrier) raises likely systemic exposure to high. ([echa.europa.eu](https://echa.europa.eu/et/brief-profile/-/briefprofile/100.003.551?utm_source=openai))
VeriMom은 methoxydiglycol을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 methoxydiglycol을 13/100 (높은 위험)로 평가합니다.
임신 중 methoxydiglycol 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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