임신 중 melamine을 피해야 할까요? | VeriMom
Melamine (CAS 108-78-1) is flagged by ECHA/REACH processes (candidate SVHC; SDSs/ECHA listings show H361f in some notices) and animal studies report embryo/fetotoxic and reproductive effects at high oral doses in rodents, so it meets “suspected” reproductive hazard (H361-level). Mechanistic work (rodent and in vitro studies) shows effects on oocytes, placental/fetal growth and increased apoptosis, supporting a demonstrated mechanism. Dermal/topical exposure from cosmetics is expected to give low but measurable systemic exposure (dermal absorption described as poor in some assessments but not zero), so exposure score is low (1). Sources: ECHA listing, Canada/ECCC human-health update, NTP and peer-reviewed developmental/reproductive studies.
ECHA regulatory hazard statements
- •H351
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- melamine은 임신 중 안전한가요?
- Melamine (CAS 108-78-1) is flagged by ECHA/REACH processes (candidate SVHC; SDSs/ECHA listings show H361f in some notices) and animal studies report embryo/fetotoxic and reproductive effects at high oral doses in rodents, so it meets “suspected” reproductive hazard (H361-level). Mechanistic work (rodent and in vitro studies) shows effects on oocytes, placental/fetal growth and increased apoptosis, supporting a demonstrated mechanism. Dermal/topical exposure from cosmetics is expected to give low but measurable systemic exposure (dermal absorption described as poor in some assessments but not zero), so exposure score is low (1). Sources: ECHA listing, Canada/ECCC human-health update, NTP and peer-reviewed developmental/reproductive studies.
- melamine은 모유 수유 중 안전한가요?
- Same hazard and mechanism rationale as pregnancy (animal reproductive and perinatal effects; mechanistic studies). For topical cosmetic use systemic levels are expected to be low but measurable, so breastmilk transfer potential is low but possible—exposure scored 1 in absence of specific lactation transfer data.
- melamine은 아기 피부에 안전한가요?
- Hazard and mechanistic evidence come from the same animal and in vitro literature and support ‘suspected’ reproductive/developmental toxicity. Dermal exposure for infants is assigned one tier higher than adults because infant skin is more permeable; therefore exposure is increased to 2 (moderate) if the ingredient has measurable absorption. There is no infant-specific toxicokinetic evidence to change hazard/mechanism scores.
- VeriMom은 melamine을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 melamine을 20/100 (높은 위험)로 평가합니다.
- 임신 중 melamine 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.